Paper ID: 2211.16161

Artifact Removal in Histopathology Images

Cameron Dahan, Stergios Christodoulidis, Maria Vakalopoulou, Joseph Boyd

In the clinical setting of histopathology, whole-slide image (WSI) artifacts frequently arise, distorting regions of interest, and having a pernicious impact on WSI analysis. Image-to-image translation networks such as CycleGANs are in principle capable of learning an artifact removal function from unpaired data. However, we identify a surjection problem with artifact removal, and propose an weakly-supervised extension to CycleGAN to address this. We assemble a pan-cancer dataset comprising artifact and clean tiles from the TCGA database. Promising results highlight the soundness of our method.

Submitted: Nov 29, 2022