Paper ID: 2409.10422

Learning Semi-Supervised Medical Image Segmentation from Spatial Registration

Qianying Liu, Paul Henderson, Xiao Gu, Hang Dai, Fani Deligianni

Semi-supervised medical image segmentation has shown promise in training models with limited labeled data and abundant unlabeled data. However, state-of-the-art methods ignore a potentially valuable source of unsupervised semantic information -- spatial registration transforms between image volumes. To address this, we propose CCT-R, a contrastive cross-teaching framework incorporating registration information. To leverage the semantic information available in registrations between volume pairs, CCT-R incorporates two proposed modules: Registration Supervision Loss (RSL) and Registration-Enhanced Positive Sampling (REPS). The RSL leverages segmentation knowledge derived from transforms between labeled and unlabeled volume pairs, providing an additional source of pseudo-labels. REPS enhances contrastive learning by identifying anatomically-corresponding positives across volumes using registration transforms. Experimental results on two challenging medical segmentation benchmarks demonstrate the effectiveness and superiority of CCT-R across various semi-supervised settings, with as few as one labeled case. Our code is available at this https URL.

Submitted: Sep 16, 2024