AlphaFold2 Protein Structure Prediction

AlphaFold2, a revolutionary deep learning model, has dramatically improved the accuracy of protein structure prediction from amino acid sequences, often rivaling experimental methods. Current research focuses on enhancing AlphaFold2's capabilities, including improving its prediction of protein complexes and binding sites, addressing limitations in handling mutations and low-homology targets, and developing more efficient implementations for wider accessibility. These advancements are accelerating drug discovery, enabling more precise structure-based drug design, and facilitating broader biological research by providing readily available, accurate protein structure information.

Papers