Alzheimer'S Disease
Alzheimer's disease (AD) research focuses on improving early and accurate diagnosis to facilitate timely intervention. Current efforts utilize diverse data sources (MRI, EEG, speech, genetics) and advanced machine learning models, including convolutional neural networks (CNNs), transformers, and Bayesian networks, to identify disease biomarkers and predict progression. These advancements aim to enhance diagnostic accuracy, personalize treatment strategies, and ultimately improve patient outcomes, though challenges remain in data standardization, model interpretability, and generalizability across diverse populations. The integration of multimodal data and explainable AI techniques is a key trend to improve both predictive power and clinical utility.
Papers
Multimodal MRI Accurately Identifies Amyloid Status in Unbalanced Cohorts in Alzheimer's Disease Continuum
Giorgio Dolci (1, 2, 3), Charles A. Ellis (3), Federica Cruciani (2), Lorenza Brusini (2), Anees Abrol (3), Ilaria Boscolo Galazzo (2), Gloria Menegaz (2), Vince D. Calhoun (3) ((1) Department of Computer Science, University of Verona, Verona, Italy, (2) Department of Engineering for Innovation Medicine, University of Verona, Verona, Italy, (3) Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA)
An interpretable generative multimodal neuroimaging-genomics framework for decoding Alzheimer's disease
Giorgio Dolci (1, 2), Federica Cruciani (1), Md Abdur Rahaman (2), Anees Abrol (2), Jiayu Chen (2), Zening Fu (2), Ilaria Boscolo Galazzo (1), Gloria Menegaz (1), Vince D. Calhoun (2) ((1) Department of Engineering for Innovation Medicine, University of Verona, Verona, Italy, (2) Tri-Institutional Center for Translational Research in Neuroimaging and Data Science (TReNDS), Georgia State University, Georgia Institute of Technology, Emory University, Atlanta, GA, USA)
Assessing the significance of longitudinal data in Alzheimer's Disease forecasting
Batuhan K. Karaman, Mert R. Sabuncu
A Machine Learning Approach to Analyze the Effects of Alzheimer's Disease on Handwriting through Lognormal Features
Tiziana D'Alessandro, Cristina Carmona-Duarte, Claudio De Stefano, Moises Diaz, Miguel A. Ferrer, Francesco Fontanella
Gamified AI Approch for Early Detection of Dementia
Paramita Kundu Maji, Soubhik Acharya, Priti Paul, Sanjay Chakraborty, Saikat Basu
Exploring Nutritional Impact on Alzheimer's Mortality: An Explainable AI Approach
Ziming Liu, Longjian Liu, Robert E. Heidel, Xiaopeng Zhao
Augmented Risk Prediction for the Onset of Alzheimer's Disease from Electronic Health Records with Large Language Models
Jiankun Wang, Sumyeong Ahn, Taykhoom Dalal, Xiaodan Zhang, Weishen Pan, Qiannan Zhang, Bin Chen, Hiroko H. Dodge, Fei Wang, Jiayu Zhou
Cross-Modality Translation with Generative Adversarial Networks to Unveil Alzheimer's Disease Biomarkers
Reihaneh Hassanzadeh, Anees Abrol, Hamid Reza Hassanzadeh, Vince D. Calhoun
DALK: Dynamic Co-Augmentation of LLMs and KG to answer Alzheimer's Disease Questions with Scientific Literature
Dawei Li, Shu Yang, Zhen Tan, Jae Young Baik, Sukwon Yun, Joseph Lee, Aaron Chacko, Bojian Hou, Duy Duong-Tran, Ying Ding, Huan Liu, Li Shen, Tianlong Chen