Brain Structure
Brain structure research focuses on understanding the relationship between brain anatomy and cognitive function, particularly in neurological disorders like Alzheimer's disease and Down syndrome. Current investigations leverage advanced machine learning models, including generative models (like Variational Autoencoders and Diffusion Models), graph convolutional networks, and part-prototype neural networks, to analyze high-resolution brain imaging data (MRI) and extract meaningful features from both macroscopic structures and microscopic tissue properties. These analyses aim to improve diagnostic accuracy, predict disease progression, and uncover biomarkers for various neurological conditions, ultimately advancing both our understanding of the brain and the development of effective treatments.
Papers
Brain Anatomy Prior Modeling to Forecast Clinical Progression of Cognitive Impairment with Structural MRI
Lintao Zhang, Jinjian Wu, Lihong Wang, Li Wang, David C. Steffens, Shijun Qiu, Guy G. Potter, Mingxia Liu
Multi-task Collaborative Pre-training and Individual-adaptive-tokens Fine-tuning: A Unified Framework for Brain Representation Learning
Ning Jiang, Gongshu Wang, Tianyi Yan