Corneal Endothelium

The corneal endothelium, a single-cell-thick layer lining the inner cornea, is crucial for maintaining corneal transparency and health. Current research focuses on improving automated analysis of specular microscopy images, employing deep learning architectures like UNets and DenseUNets, often incorporating novel attention mechanisms, to accurately assess endothelial cell density, morphology (including guttae detection in Fuchs' dystrophy), and overall corneal health. These advancements aim to improve the objectivity and efficiency of corneal disease diagnosis and monitoring, particularly for conditions like Fuchs' dystrophy and dry eye disease, leading to better patient care and management. Improved image processing techniques, such as panoramic image generation from contact specular microscopy, are also enhancing the comprehensiveness of endothelial assessments.