Digital Pathology
Digital pathology uses digitized microscopy images to analyze tissue samples, aiming to improve diagnostic accuracy and efficiency in healthcare. Current research focuses on developing and refining deep learning models, including transformers and convolutional neural networks, to address challenges like stain variation, limited annotated data, and the need for improved model interpretability and uncertainty quantification. These advancements are leading to more robust and efficient algorithms for tasks such as image segmentation, classification, and the integration of spatial transcriptomics data, ultimately impacting clinical workflows and potentially accelerating biomarker discovery.
Papers
Segment Anything Model (SAM) for Digital Pathology: Assess Zero-shot Segmentation on Whole Slide Imaging
Ruining Deng, Can Cui, Quan Liu, Tianyuan Yao, Lucas W. Remedios, Shunxing Bao, Bennett A. Landman, Lee E. Wheless, Lori A. Coburn, Keith T. Wilson, Yaohong Wang, Shilin Zhao, Agnes B. Fogo, Haichun Yang, Yucheng Tang, Yuankai Huo
Slideflow: Deep Learning for Digital Histopathology with Real-Time Whole-Slide Visualization
James M. Dolezal, Sara Kochanny, Emma Dyer, Andrew Srisuwananukorn, Matteo Sacco, Frederick M. Howard, Anran Li, Prajval Mohan, Alexander T. Pearson
Between Generating Noise and Generating Images: Noise in the Correct Frequency Improves the Quality of Synthetic Histopathology Images for Digital Pathology
Nati Daniel, Eliel Aknin, Ariel Larey, Yoni Peretz, Guy Sela, Yael Fisher, Yonatan Savir
DEPAS: De-novo Pathology Semantic Masks using a Generative Model
Ariel Larey, Nati Daniel, Eliel Aknin, Yael Fisher, Yonatan Savir