Gene Ontology

Gene Ontology (GO) is a structured, controlled vocabulary describing the functions of genes and proteins, aiming to standardize biological knowledge representation and facilitate data analysis. Current research focuses on integrating GO with machine learning techniques, such as graph convolutional networks and large language models, to improve tasks like gene set enrichment analysis, protein function prediction, and knowledge graph construction. These advancements enhance the interpretability of high-throughput biological data, leading to more accurate and efficient biological discovery across diverse applications, including disease diagnosis and drug development.