Microscopy Image
Microscopy image analysis focuses on extracting quantitative information and insights from microscopic images across diverse scientific domains. Current research emphasizes automated segmentation and analysis using deep learning models, particularly U-Net, Vision Transformers, and the Segment Anything Model (SAM), often coupled with techniques like contrastive learning and multiple instance learning to handle noisy or incomplete data. These advancements are significantly impacting fields like biomedical research (e.g., cell tracking, disease diagnosis), materials science (e.g., defect detection), and manufacturing (e.g., quality control), enabling higher-throughput analysis and more precise measurements than traditional methods. Furthermore, research is actively addressing challenges like image denoising, super-resolution, and the development of robust metrics for evaluating model performance on microscopy-specific data characteristics.
Papers
Phenotype-preserving metric design for high-content image reconstruction by generative inpainting
Vaibhav Sharma, Artur Yakimovich
Fluorescent Neuronal Cells v2: Multi-Task, Multi-Format Annotations for Deep Learning in Microscopy
Luca Clissa, Antonio Macaluso, Roberto Morelli, Alessandra Occhinegro, Emiliana Piscitiello, Ludovico Taddei, Marco Luppi, Roberto Amici, Matteo Cerri, Timna Hitrec, Lorenzo Rinaldi, Antonio Zoccoli
Onboard Science Instrument Autonomy for the Detection of Microscopy Biosignatures on the Ocean Worlds Life Surveyor
Mark Wronkiewicz, Jake Lee, Lukas Mandrake, Jack Lightholder, Gary Doran, Steffen Mauceri, Taewoo Kim, Nathan Oborny, Thomas Schibler, Jay Nadeau, James K. Wallace, Eshaan Moorjani, Chris Lindensmith
Learning imaging mechanism directly from optical microscopy observations
Ze-Hao Wang, Long-Kun Shan, Tong-Tian Weng, Tian-Long Chen, Qi-Yu Wang, Xiang-Dong Chen, Zhang-Yang Wang, Guang-Can Guo, Fang-Wen Sun