Sequence Motif

Sequence motifs are recurring patterns in biological sequences (DNA, RNA, or protein) that play crucial roles in various biological processes. Current research focuses on developing advanced computational methods, including deep learning models like diffusion models and transformer-based architectures, to identify, predict, and utilize these motifs for tasks such as drug design, protein engineering, and gene expression prediction. These efforts leverage techniques like motif-aware masking and connection-aware motif mining to improve model accuracy and interpretability. The ability to effectively identify and understand sequence motifs has significant implications for diverse fields, including drug discovery, genomics, and materials science.