Sequential Neural
Sequential Neural Posterior Estimation (SNPE) is a machine learning approach to Bayesian inference for models with intractable likelihood functions, aiming to efficiently estimate posterior distributions of model parameters using only simulated data. Current research focuses on improving SNPE's efficiency and robustness through techniques like adaptive calibration kernels, multi-level Monte Carlo methods, and the use of normalizing flows to handle high-dimensional data, often incorporating neural networks for density estimation. These advancements enable SNPE to tackle complex scientific problems, such as exoplanet atmospheric retrieval and Bayesian system identification, where traditional methods struggle due to computational cost or model complexity. The resulting speed and accuracy improvements are significantly impacting various fields by allowing for more sophisticated model usage and more reliable uncertainty quantification.