Synthetic Histopathology Image
Synthetic histopathology image generation aims to create realistic digital representations of tissue samples, addressing the limitations of acquiring and annotating large, diverse datasets for training AI models in digital pathology. Current research heavily utilizes diffusion models and generative adversarial networks (GANs), often incorporating transformers or convolutional neural networks, to generate images at various scales, from individual nuclei to whole slide images, sometimes conditioned on semantic masks or class labels. This technology offers significant potential for augmenting existing datasets, improving the performance of AI algorithms for disease classification and nuclei segmentation, enhancing data privacy, and facilitating educational applications in pathology.
Papers
Between Generating Noise and Generating Images: Noise in the Correct Frequency Improves the Quality of Synthetic Histopathology Images for Digital Pathology
Nati Daniel, Eliel Aknin, Ariel Larey, Yoni Peretz, Guy Sela, Yael Fisher, Yonatan Savir
DEPAS: De-novo Pathology Semantic Masks using a Generative Model
Ariel Larey, Nati Daniel, Eliel Aknin, Yael Fisher, Yonatan Savir