MALDI ToF

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-ToF) is a powerful technique used to analyze the mass-to-charge ratio of molecules, primarily for protein identification and imaging in biological samples. Current research focuses on improving data analysis, particularly through advanced algorithms like topological data analysis and fuzzy systems, to enhance signal processing, noise reduction, and the identification of isotopic envelopes in high-dimensional datasets. These advancements are crucial for applications such as cancer subtyping and improved diagnostic capabilities, enabling more precise and efficient analysis of complex biological samples.