ASPEN: Spectral-Temporal Fusion for Cross-Subject Brain Decoding

The development of generalizable electroencephalography (EEG) decoding models is essential for robust brain-computer interfaces (BCI) and objective neural biomarkers in mental health. Conventional approaches have been hindered by poor cross-subject and cross-task generalization, owing to high inter-subject variability and non-stationary neural signals. We address this challenge with a zero-shot cross-subject decoding framework on the large-scale Healthy Brain Network dataset, benchmarking a convolutional neural network baseline, a hybrid LSTM, and a Transformer-based foundation model. To adapt the Transformer for regression while averting catastrophic forgetting, we propose a novel progressive unfreezing strategy. The baseline yielded an nRMSE of 0.9991, whereas our fine-tuned Transformer achieved 0.9799 on unseen subjects. This work advances scalable, calibration-free EEG decoding for computational psychiatry and behavioral prediction.

In cross-subject EEG emotion decoding, neighboring windows can inform the representation of a target window, but they contain both background variation and sustained task signals. This creates a challenge for contextual representation learning because subtracting shared activity can also remove useful information. We introduce the Morlet Spectral Transformer (MST), which conditions target-window tokens on a structured spectral summary before attention. MST averages the Morlet log-amplitude spectra of unlabeled same-trial neighbors and uses frequency-specific electrode projections to combine the target spectrum with its reference-relative residual. This retains access to absolute activity while incorporating context into a fixed attended target-token grid. Without external pretraining, MST achieves 66.5%, 40.7%, 36.1%, and 27.9% accuracy on SEED, SEED-IV, SEED-V, and SEED-VII under leave-one-subject-out evaluation, averaged over three random seeds, outperforming the evaluated pretrained and from-scratch baselines. On FACED, MST achieves 17.52% accuracy in nine-class cross-subject evaluation, exceeding the strongest evaluated baseline by 1.15 percentage points. We also performed the ablation studies across all 15 SEED subjects to evaluate the contribution of different components of MST.

Personalised music-based interventions offer a powerful means of supporting motor rehabilitation by dynamically tailoring auditory stimuli to provide external timekeeping cues, modulate affective states, and stabilise gait patterns. Generalisable Brain-Computer Interfaces (BCIs) thus hold promise for adapting these interventions across individuals. However, inter-subject variability in EEG signals, further compounded by movement-induced artefacts and motor planning differences, hinders the generalisability of BCIs and results in lengthy calibration processes. We propose Individual Tangent Space Alignment (ITSA), a novel pre-alignment strategy incorporating subject-specific recentering, distribution matching, and supervised rotational alignment to enhance cross-subject generalisation. Our hybrid architecture fuses Regularised Common Spatial Patterns (RCSP) with Riemannian geometry in parallel and sequential configurations, improving class separability while maintaining the geometric structure of covariance matrices for robust statistical computation. Using leave-one-subject-out cross-validation, `ITSA' demonstrates significant performance improvements across subjects and conditions. The parallel fusion approach shows the greatest enhancement over its sequential counterpart, with robust performance maintained across varying data conditions and electrode configurations. The code will be made publicly available at the time of publication.