Measuring Psychological States Through Semantic Projection: A Theory-Driven Approach to Language-Based Assessment

Natural Language Processing (NLP) models predicting mental health outcomes rarely specify what they measure: contextual knowledge, emotional content, or syntactic structure. NLP Psychometrics treats psychological prediction from text as a psychometric problem, linking scores to interpretable linguistic evidence and testing beyond the training text format. Nine LLMs, conditioned on controlled personas (cognitive digital shadows), completed psychometric questionnaires with textual explanations per item. We extracted emotional profiles and syntactic-semantic structure via textual forma mentis networks, combined with personality and sociodemographic variables in ablated random forest (RF) regressors, using SHAP to identify which features drove performance and in which direction. Full RF models explained up to 70.8% of variance in life satisfaction (SWLS), 55.7% in depression (PHQ-9), and, for DASS-21, 68.5% depression, 76.0% anxiety, 72.4% stress. Sociodemographics alone explained no meaningful variance in depression, anxiety, or stress, but did so for life satisfaction, where emotion features and income were the strongest predictors; neuroticism and network topology instead dominated depression and anxiety, reversing direction between them. Without retraining, RF models separated diaries from low- and high-score personas ($r$ up to 0.91) and, using only network/emotion features, classified clinical from control participants in real transcripts with up to 68% accuracy. These results show the promise and limits of synthetic data: LLM personas can expose model biases, recover patterns consistent with clinical rumination, and support psychometric prediction from human text without a matched questionnaire, but cannot substitute for human validation. NLP Psychometrics makes these distinctions explicit, measurable, and testable through interpretable AI and network/emotional features.

Patients with depression present with diverse symptom profiles, yet clinical practice routinely reduces this variation to a single severity score. Large language models (LLMs) can potentially capture various symptoms and their severity from patient speech. However, how depressive symptoms are represented inside LLMs remains poorly understood, limiting clinical trust. To examine whether internal model activations match clinician judgment, we analyzed the residual stream of Gemma-3-27B-PT using mechanistic interpretability techniques. Recording activations across symptom descriptions drawn from validated clinical instruments, we found that symptom groups geometrically separated the most at layer 21 across multiple distance metrics. Using Semantic Projection, we then projected held-out naturalistic text onto Symptom Vectors constructed from these instruments. The resulting per-symptom coefficients preserved clinician-annotated rank ordering across mood, somatic, and suicidality axes. Furthermore, a single depression vector in Layer 21 separates held-out depressive from non-depressive text (AUC = 0.789), which can be used as an emotional valence gate that restricts symptom projection to depressive speech. These results reveal a decorrelated, clinician-aligned symptom signal readable directly from internal activations, offering a mechanistic foundation for interpretable depression-assessment tools.

Self-report questionnaires remain the prevailing tool for probing the psychological states of persona-conditioned agents (PC-Agents). However, classical instruments inherit two well-known threats: contamination from training corpora and directional bias driven by social-desirability or contextual framing. To overcome these methodological bottlenecks, we ask whether projective paradigms can be adapted into a robust psychometric tool. We introduce \textbf{GenPT} (Generative Projective Testing), which reformulates TAT, Rorschach, and SCT with newly generated stimuli and organizes assessment as a three-stage pipeline to derive standardized psychological indicators and target states. Evaluating PC-Agents induced via CharacterRAG and AnnaAgent profiles, we benchmark GenPT's reliability and validity against classical questionnaires. The results indicate that questionnaires exhibit systematic directional shifts under social-desirability framing, most strongly on suicide ideation. In contrast, GenPT's collected behavioral patterns stay near the symmetric baseline. Furthermore, under a longitudinal counselling context, GenPT-based depression assessment shifts by roughly an order of magnitude more than the questionnaire counterpart when Qwen3 serves as the backbone. Overall, GenPT complements self-report methods in scenarios where contamination resistance, bias asymmetry, and context sensitivity matter. Code and stimuli can be found at https://github.com/sci-m-wang/GenPT.