MAIL++: Multi-Modal Bi-directional Agent Layer for Vision-Language Models

Prompt learning has become a dominant paradigm for adapting vision-language models (VLMs) such as CLIP to downstream tasks without modifying pretrained weights. While extending prompts to both vision and text encoders across multiple transformer layers significantly boosts performance, it dramatically increases the number of trainable parameters, with state-of-the-art methods requiring millions of parameters and abandoning the parameter efficiency that makes prompt tuning attractive. In this work, we propose MMLoP (Multi-Modal Low-Rank Prompting), a framework that achieves deep multi-modal prompting with only 11.5K trainable parameters, comparable to early text-only methods like CoOp. MMLoP parameterizes vision and text prompts at each transformer layer through a low-rank factorization that constrains prompts to a compact subspace, providing parameter efficiency while motivating the need for our complementary regularization components. To further close the accuracy gap with state-of-the-art methods, we introduce three complementary components: a self-regulating consistency loss that anchors prompted representations to frozen zero-shot CLIP features at both the feature and logit levels, a uniform drift correction that removes the global embedding shift induced by prompt tuning to preserve class-discriminative structure, and a shared up-projection that couples vision and text prompts through a common low-rank factor to enforce cross-modal alignment. Extensive experiments across three benchmarks and 11 diverse datasets demonstrate that MMLoP achieves a highly favorable accuracy-efficiency tradeoff, outperforming the majority of existing methods including those with orders of magnitude more parameters, while achieving a harmonic mean of 79.70% on base-to-novel generalization. Code is available at https://github.com/sajjad-ucsb/MMLoP.

Vision-Language Models (VLMs) create a severe visual feature bottleneck by using a crude, asymmetric connection that links only the output of the vision encoder to the input of the large language model (LLM). This static architecture fundamentally limits the ability of LLMs to achieve comprehensive alignment with hierarchical visual knowledge, compromising their capacity to accurately integrate local details with global semantics into coherent reasoning. To resolve this, we introduce Cross-Layer Injection (CLI), a novel and lightweight framework that forges a dynamic many-to-many bridge between the two modalities. CLI consists of two synergistic, parameter-efficient components: an Adaptive Multi-Projection (AMP) module that harmonizes features from diverse vision layers, and an Adaptive Gating Fusion (AGF) mechanism that empowers the LLM to selectively inject the most relevant visual information based on its real-time decoding context. We validate the effectiveness and versatility of CLI by integrating it into LLaVA-OneVision and LLaVA-1.5. Extensive experiments on 18 diverse benchmarks demonstrate significant performance improvements, establishing CLI as a scalable paradigm that unlocks deeper multimodal understanding by granting LLMs on-demand access to the full visual hierarchy.

Computer-aided medical image analysis is crucial for disease diagnosis and treatment planning. While vision-language models (VLMs) such as CLIP exhibit strong generalization ability, their direct application to medical imaging remains hindered by a substantial domain gap. Existing methods for bridging this gap, including prompt learning and unidirectional modality interaction, typically introduce domain knowledge into only one modality. However, such approaches fail to fully exploit CLIP's inherent dual-modality structure and overlook the synergistic effect of bidirectional cross-modal interaction, resulting in persistent modality misalignment. In this paper, we propose NEARL (iNteracted quEry Adaptation with oRthogonaL Regularization), a novel parameter-efficient VLM framework for bidirectional cross-modal interaction. NEARL consists of two key components: (1) the Unified Synergy Embedding Transformer (USEformer), which dynamically generates compact cross-modal queries to facilitate interaction; and (2) the Orthogonal Cross-Attention Adapter (OCA), which decouples new knowledge into truly novel and incremental components through orthogonal regularization. This design reduces interference from incremental components, enabling more focused learning of novel information and improving modality interaction in VLMs. Notably, NEARL introduces only 1.46M learnable parameters. Extensive experiments on three medical imaging modalities demonstrate state-of-the-art performance (e.g., a 2.3% relative improvement on the pneumonia dataset), along with fast inference and low memory overhead, highlighting its effectiveness for real-world medical vision-language understanding.