S^{2}-FracMix: Label-Preserving Self-Saliency Mixup Augmentation

In image and video technologies, data augmentation is widely used to improve the generalization of deep visual models, and mixup-based strategies that interpolate between samples have become the dominant approach. However, computing informative mixing regions adds substantial overhead, and blending content across different images frequently disrupts the semantic integrity of the resulting sample. We propose \our{}, a data augmentation method that constructs challenging yet label-consistent training samples entirely within a single visual sample. \our{} first extracts multi-scale salient patches from the sample using a lightweight saliency detector, refines each patch with an instruction-guided generative model, and blends the edited patch back into the non-salient regions of the same sample; because the generative edits are computed once and cached offline, this step adds negligible training cost. To further diversify the learned representation, \our{} injects self-similar fractal structure into the same salient regions at an adaptive ratio, so each training sample carries both fractal and non-fractal structure. We derive a second-order approximation of the resulting vicinal risk, showing that the method simultaneously enforces invariance to the generative edit and suppresses curvature along the perturbed salient directions, and we verify both predictions empirically. We evaluate on small to large backbones for instance Convolutional Neural Networks (CNNs), Vision Transformers (ViTs) and Vision-Language Foundational Models (VLMs) across seven benchmarks covering coarse- and fine-grained classification, robustness to corruption and occlusion, calibration, and transfer and self-supervised learning, InstructMixup outperforms nine competing augmentation methods, surpassing the strongest baseline across all benchmarks.

Multimodal large language models (MLLMs) have achieved remarkable performance across vision-language tasks, but their progress depends heavily on large-scale, high-quality multimodal data that are costly to annotate. Self-augmentation offers a promising alternative by enabling models to expand their own training data without external supervision. However, existing MLLM self-augmentation methods are largely text-centric, while image augmentation remains underexplored and typically relies on generic or handcrafted transformations that are weakly aligned with the model's actual incapability. We propose Failure-informed Image Self-Augmentation (\textbf{FISA}), a framework for MLLM self-improvement that constructs augmented images from the model's own failure cases. Our method generates visually challenging yet answer-preserving image complications, verifies their utility through self-examination, and applies dual fidelity filtering to avoid semantic distortion. Experiments on visual question answering benchmarks show that the proposed method consistently improves performance across both in-distribution and out-of-distribution settings. Further experiments validate the compatibility of FISA with existing textual self-augmentation approaches, the superior data efficiency of the synthesized samples over generic image augmentation baselines, and the practical effectiveness of the proposed filtering strategy.

Limited data availability, class imbalance, and domain variability remain major barriers to reliable medical image classification. Conventional augmentation can improve training diversity but may distort diagnostically informative structures, whereas unconstrained generative augmentation may introduce label-inconsistent content. This paper proposes MedDiffuseMix, a saliency-guided diffusion mixing framework for controlled medical image augmentation. The method uses classifier-derived saliency maps to separate high-saliency diagnostic regions from low-saliency background areas and applies diffusion-guided mixing mainly to regions with lower diagnostic importance. Adaptive mixing, Gaussian boundary blending, and a saliency-preservation constraint reduce semantic distortion and reject or attenuate samples that shift model attention away from clinically relevant evidence. The framework is evaluated on four public benchmarks: the Radiological Society of North America pneumonia chest radiography dataset, Musculoskeletal Radiographs, PatchCamelyon, and the Breast Cancer Histopathological Image Classification dataset. Experiments with convolutional and transformer-based classifiers show that MedDiffuseMix improves accuracy, F1-score, and area under the receiver operating characteristic curve compared with standard augmentation, Mixup, GenMix, SaliencyMix, and diffusion-based augmentation baselines. Ablation studies confirm the importance of saliency guidance, adaptive region mixing, and smooth boundary blending. Visual attribution analysis further indicates that MedDiffuseMix better preserves diagnostically salient regions. These results suggest that saliency-guided diffusion mixing is an effective augmentation strategy for limited-data medical image classification.