Automated Data Readiness for Scientific AI

AI for Science (AI4Science) workflows often treat the released dataset as a fixed interface to the underlying system. However, in domains relying on \emph{indirect observation}, the learner observes a derivative representation produced by multi-stage measurement, reconstruction, and preprocessing pipelines. \textbf{We argue that these measurement-to-dataset pipelines are inference components: treating their outputs as given data'' freezes an observation model and obscures uncertainty over feasible pipeline choices.} We identify three failure modes arising from this frozen lens'': \textbf{(C1) hidden hypothesis space}, where the released dataset does not specify the pipeline configuration or its validity conditions; \textbf{(C2) uncertified transportability}, where a pipeline may be documented but its regime of validity is untested, so failures under distribution shift cannot be adjudicated; \textbf{(C3) ungoverned multiplicity}, where many defensible pipelines exist and dispersion is real but not propagated into uncertainty-aware evidence. We stress-test these claims with a large-scale neuroscience empirical audit, finding a survival rate of $\approx 0.0004\%$ under a cross-dataset stability criterion. We call on the AI4Science community to make pipelines \emph{computable} inference objects via domain-specific Computable Observation Frameworks. This shift enables quantifying pipeline adequacy and stability, converting implicit implementation choices into auditable, reproducible, and cumulative scientific evidence.

AI-for-Science (AI4Science) is increasingly transforming scientific discovery by embedding machine learning models into prediction, simulation, and hypothesis generation workflows across domains. However, the effectiveness of these models is fundamentally constrained by the AI-readiness of scientific data, for which no scalable and systematic evaluation mechanism currently exists. In this work, we propose SciHorizon-DataEVA, a novel agentic system to scalable AI-readiness evaluation of heterogeneous scientific data. At the evaluation-criteria level, we introduce the Sci-TQA2 principles, which organize AI-readiness into four complementary dimensions: Governance Trustworthiness, Data Quality, AI Compatibility, and Scientific Adaptability. Each dimension is decomposed into measurable atomic elements that enable fine-grained and executable assessment. To operationalize these principles at scale, we develop Sci-TQA2-Eval, a hierarchical multi-agent evaluation approach orchestrated through a directed, cyclic workflow. Our Sci-TQA2-Eval dynamically constructs dataset-aware evaluation specifications by combining lightweight dataset profiling, applicability-aware metric activation, and knowledge-augmented planning grounded in domain constraints and dataset-paper signals. These specifications are executed through an adaptive, tool-centric evaluation mechanism with built-in verification and self-correction, enabling scalable and reliable assessment across heterogeneous scientific data. Extensive experiments on scientific datasets spanning multiple domains demonstrate the effectiveness and generality of SciHorizon-DataEVA for principled AI-readiness evaluation.

The rapid growth of Artificial Intelligence and Machine Learning in scientific research has highlighted a gap between industry-standard MLOps tools and platforms, and the unique requirements of modern and Open Science, particularly regarding the FAIR (Findable, Accessible, Interoperable, and Reusable) principles. This paper presents AI4EOSC, a federated, open-source platform designed to operationalize the full AI/ML lifecycle within the European Open Science Cloud (EOSC) ecosystem. Our methodology tackles the fragmentation of distributed research infrastructures by integrating a modular and distributed architecture comprising an AI development platform, a serverless AI-as-a-Service layer, and a federated orchestration model that is able to integrate heterogeneous compute and storage resources from distributed e-Infrastructures. AI4EOSC also introduces a ``FAIR-by-design'' approach that enforces metadata standardization (via MLDCAT-AP) and W3C PROV-compliant provenance tracking through a platform-integrated CI/CD pipeline. AI4EOSC added value is demonstrated through the delivery of a diverse set of community installations, showing consistent and seamless deployment across heterogeneous cloud providers. These installations are validated by a set of scientific cases, showing how our work reduces the manual burden on researchers while ensuring high levels of reproducibility and interoperability and providing an unified environment for development, training, and production of AI/ML models in the EOSC.