MXSens: Sensitivity-Aware Mixed-Precision Quantization for Efficient LLM Inference

Quantizing large language models (LLMs) to low-precision floating-point representations is central to efficient deployment, yet applying a single bit-width uniformly across all layers is sub-optimal in terms of both performance and accuracy. This work introduces dMX, a differentiable mixed-precision quantization framework for learnable floating-point bit-width assignment. We study its application for the microscaling floating-point (MXFP) family of data types defined by the Open Compute Project (OCP) standard. The per-layer bit-width assignment is formulated as a continuous optimization problem in which each layer's floating-point format format is parameterized by a scalar parameter, folding the multi-variate design space into a single learnable offset. During training this offset takes continuous values, avoiding sudden oscillations between discrete quantization formats. A temperature-based annealing schedule progressively discretizes the learned offsets, ensuring that the final configuration maps to hardware-compatible MXFP formats without abrupt transitions between training and inference behavior. A target-aware regularization term steers the average bit-width toward a user-specified budget, serving as a coarse-grained proxy for inference cost and balancing model quality against deployment efficiency. We performed experiments on different families of LLM, such as Llama, Qwen3, and SmolLM2, evaluating perplexity on WikiText-2 and accuracy on four zero-shot reasoning benchmarks. Across these settings, dMX consistently yields Pareto-dominating models and improves over Kullback-Leibler (KL) divergence-based layer-selection heuristics, efficiently navigating trade-offs between model quality and average bit-width.

Mixed-precision quantization (MPQ) has become a key technique for deploying large language models under stringent memory and compute constraints. We first identify a phenomenon that we term the Perplexity Illusion: layers ranked as important by perplexity-based sensitivity show little rank correlation with those that are most influential for complex reasoning performance, with Kendall $τ\approx 0$ in our analysis. We further reveal an Alignment-Diversity Tradeoff: using only target-task calibration data can degrade post-quantization performance, whereas incorporating general-domain data stabilizes sensitivity estimation and improves robustness across tasks. Based on these observations, we propose TASA (Task-Aware Sensitivity Analysis), a two-level framework that jointly optimizes calibration-data composition and mixed-precision bit allocation. Specifically, TASA searches for a calibration-data mixture using a training-free gradient-trace alignment criterion, and then aggregates perplexity and reasoning-oriented sensitivity signals to guide both inter-layer and intra-layer bit allocation. Experiments on LLaMA-3-8B and Qwen2.5-7B reveal a precision inversion: appropriately allocated 3.5-bit models can match or surpass less task-aware 4-bit baselines. At an average precision of 3.5 bits, TASA matches or outperforms several competitive 4-bit uniform baselines in aggregate accuracy, and improves over the strongest W3 baseline on GSM8K by more than 20 absolute points on LLaMA-3-8B. These results show that calibration-data composition substantially affects task-sensitive quantization, a factor underexplored in prior work.

Mixed-precision quantization improves the accuracy of post-training quantization by allocating higher bitwidths to sensitive layers, but existing methods solve the allocation for a single fixed memory budget. In practice the budget varies across deployments and is unknown at calibration time. Adaptive quantization addresses this with one offline calibration that serves any budget, yet current methods score layer sensitivity in a manner that does not consider its dependency on quantization levels of other layers. We show that a layer's sensitivity depends strongly on the bitwidths of its upstream layers and that this dependence shifts the resulting preferred bit allocation. We propose MixQuant, a technique-agnostic adaptive framework that wraps any base quantizer. MixQuant marginalizes each layer's distortion over random quantized upstream configurations to obtain budget-agnostic scores, calibrates the quantizer's parameters on plans the allocator itself produces, and penalizes allocations that leave layers at the lowest bitwidths. A single greedy pass then serves any budget at deployment. Across Llama-3.2-3B, Llama-2-7B, and Mistral-7B under AWQ and GPTQ, MixQuant outperforms adaptive and mixed-precision baselines in every setting, improving average accuracy by up to 8 points and reducing perplexity from 12.43 to 10.70 at the tightest budget, while matching an ILP solver at negligible deployment cost.