Harnessing Domain Specialists in Multimodal Mixture-of-Experts for Efficient Adaptation

Large language models are typically deployed as monolithic systems, requiring the full model even when applications need only a narrow subset of capabilities, e.g., code, math, or domain-specific knowledge. Mixture-of-Experts (MoEs) seemingly offer a potential alternative by activating only a subset of experts per input, but in practice, restricting inference to a subset of experts for a given domain leads to severe performance degradation. This limits their practicality in memory-constrained settings, especially as models grow larger and sparser. We introduce EMO, an MoE designed for modularity-the independent use and composition of expert subsets-without requiring human-defined priors. Our key idea is to encourage tokens from similar domains to rely on similar experts. Since tokens within a document often share a domain, EMO restricts them to select experts from a shared pool, while allowing different documents to use different pools. This simple constraint enables coherent expert groupings to emerge during pretraining using document boundaries alone. We pretrain a 1B-active, 14B-total EMO on 1T tokens. As a full model, it matches standard MoE performance. Crucially, it enables selective expert use: retaining only 25% (12.5%) of experts incurs just a 1% (3%) absolute drop, whereas standard MoEs break under the same setting. We further find that expert subsets in EMO specialize at semantic levels (e.g., domains such as math or code), in contrast to the low-level syntactic specialization observed in standard MoEs. Altogether, our results demonstrate a path toward modular, memory-efficient deployment of large, sparse models and open new opportunities for composable architectures.

Real-world model deployment across multiple domains requires multimodal models to operate under two complementary regimes: (1) multi-task pretraining, tasks are co-available at design time where related tasks could borrow representational strength from one another, (2) continual adaptation, in which new tasks emerge after deployment with previously unseen modality combinations. However, neither regime alone suffices: the pretraining task set is never exhaustive, while bypassing joint training forfeits the transfer gains and efficiency among co-trainable tasks. Sparse Mixture-of-Experts (MoE) is a natural fit for this dual requirement: sparse activation enables modular capacity expansion as new tasks arrive, while routing decouples modality-level computation from task-level composition. In this work, we propose a scalable MoE framework for multitask pretraining and continual learning across flexible modality combinations. The framework is designed to support training on multimodal tasks with diverse modality configurations by leveraging modality-specific routers that process tokens from each modality across tasks. Furthermore, it enables continual learning over sequential multimodal tasks within a fixed-capacity MoE by compressing accumulated expert knowledge into low-rank memory subspaces, while expanding only the lightweight routers. We validate the effectiveness of our method on multiple healthcare multimodal benchmarks. It demonstrates competitive multitask pretraining performance while alleviating catastrophic forgetting and improving parameter efficiency.

Mixture-of-Experts (MoE) has become a prevalent backbone for large vision-language models (VLMs), yet how modality-specific signals should guide expert routing remains under-explored. Existing routing strategies are either hand-crafted or modality-agnostic, relying on idealized priors that ignore the layer-dependent modality fusion patterns in MoE-VLMs and provide little guidance for expert specialization. We propose Soft Modality-guided Expert Specialization (SMoES), which consists of dynamic soft modality scores that capture layer-dependent fusion patterns, an expert binning mechanism aligned with expert-parallel deployment, and an inter-bin mutual information regularization that encourages coherent modality specialization. Our method leverages attention-based or Gaussian-statistics modality scores to optimize mutual information regularization. Experiments across four MoE-based VLMs and 16 benchmarks demonstrate improvement on both effectiveness and efficiency: 0.9% and 4.2% average gain on multimodal and language-only tasks, 56.1% reduction in EP communication overhead, and 12.3% throughput improvement under realistic deployment. These results validate that aligning routing with modality-aware expert specialization unlocks MoE-VLM capacity and efficiency.