cs.AIOct 26, 2026

CohortFlow: A Steerable Clinical Cohort Curation Agent with Localized Semantic Correction

Authors: Neil Chen, Adrian Serapio, Hanxue Gu, Evan Lee, Kang Wang, Yang Yang

Organizations: UC Berkeley · UC San Francisco

Abstract

Language model agents for clinical cohort curation should accommodate evolving eligibility criteria without repeatedly processing unchanged requirements. We introduce CohortFlow, a steerable agent that represents natural language corrections as localized updates to a structured cohort specification and reconciles them with a persistent execution graph. Explicitly recorded semantic dependencies enable affected computations to be selectively invalidated while preserving valid prior results. On 100 scenarios derived from clinical-trial eligibility criteria, comprising 126 correction turns, localized steering achieves 77.0% requirement micro-F1 versus 76.4% for full regeneration using the same 8B model, a small numerical advantage that is not statistically significant (p=0.493p=0.493). It reduces mean correction latency by 64.8% after completion and 44.3% during execution, with 38.1% fewer model calls. In a separate proof-of-concept evaluation over MIMIC, all 13 cohort states execute successfully, while correction trajectories demonstrate selective preservation of unaffected computations and recomputation of changed or dependent nodes. Together, these results show that localized semantic steering can substantially reduce correction latency and model calls while maintaining strong requirement-level accuracy.

Figures & tables

Appendix figures & tables2 assets

Supplementary material from the paper’s appendix.

Appendix

Explore similar work

Jul 28, 2026

COVENANT: Natural-Language Workflow Compilation for Aligned Agent Execution

Large language model (LLM) agents are increasingly entrusted with natural-language workflow instructions (e.g., retail-payment policies) that specify not only what outcome to achieve, but also which steps, branches, and tool interactions are permitted. When these instructions are supplied as prompt context, however, the model retains control over both procedure selection and step execution. As interactions accumulate, an agent can skip required steps, take unsupported branches, or execute a valid step with unsupported arguments or effects--a failure mode we call workflow misalignment. In this work, we propose COVENANT, a compiler-and-interpreter architecture for workflow-aligned agent execution. Our key insight is to treat workflow instructions as source programs rather than prompts. COVENANT converts the instructions into a workflow abstract syntax tree (WAST) and lowers it to a workflow control-flow graph (WCFG). At runtime, a controller interprets the WCFG one node at a time, checks each proposal against requirements extracted from the instructions before committing controller state or advancing the graph, and returns diagnostic feedback for repair. To evaluate COVENANT, we use 120 cases from three existing benchmarks, spanning seven workflow scenarios. Compared with state-of-the-art LLM agents, COVENANT improves benchmark success from 50.00% to 83.33% and reduces the workflow-misalignment failure rate from 42.50% to 15.83% (62.75% relative). These results show that COVENANT substantially mitigates workflow misalignment, moving LLM-agent alignment beyond isolated prompt following toward reliable execution of complex and multi-step workflows.
May 25, 2026

CausalFlow: Causal Attribution and Counterfactual Repair for LLM Agent Failures

Large language model (LLM) agents frequently fail on multi-step tasks involving reasoning, tool use, and environment interaction. While such failures are typically logged or retried heuristically, they contain structured signals about where execution broke down. We introduce CausalFlow, an interventional framework that converts failed agent traces into minimal counterfactual repairs and reusable supervision. CausalFlow models execution traces as sequential chains of dependent steps and computes Causal Responsibility Scores(CRS) via step-level counterfactual intervention to identify failure-inducing steps. For these steps, we generate minimally edited repairs that flip the final outcome to success, producing validated contrastive pairs of the form (wrong step, corrected step). CausalFlow supports two complementary uses: targeted test-time repair that recovers from failures with minimal behavioral drift, and training-time supervision suitable for offline preference optimization or reward modeling. Across four benchmarks spanning mathematical reasoning, code generation, question answering, and medical browsing, CausalFlow converts failed executions into validated minimal repairs with high minimality and causal-consensus scores, and demonstrates that causal attribution is necessary for reliable improvement across diverse agent tasks, outperforming heuristic refinement in complex retrieval settings while producing more localized repairs throughout. These results demonstrate that interventional analysis over structured execution traces provides a principled and scalable mechanism for transforming agent failures into reliability gains and learning-ready supervision.
Jul 7, 2026

CurateEvo: Data-Curation Evolving for Agentic Post-Training

Large language model (LLM) agents require post-training methods that can improve long-horizon decision making from environment feedback. However, existing agentic post-training pipelines often treat data curation as a fixed preprocessing step, focusing mainly on data augmentation while neglecting filtering, refinement, and adaptation to downstream failures. We propose CurateEvo, a failure-driven dynamic evolution framework for agentic post-training data curation. CurateEvo represents the curation strategy as executable code and iteratively rewrites it using failed trajectories from a held-out development set. At each epoch, the evolved strategy transforms a fixed raw corpus into supervised fine-tuning data, reinforcement learning data, and an inference-time memory bank. The evolution process first improves effectiveness by diagnosing recurring failure modes and augmenting, filtering, or refining data accordingly, and then improves efficiency by pruning redundant or low-utility training turns under a cost-aware objective. Experiments on ACEBench-Agent, BFCL-V4, and τ^2-Bench under both labeled and wild-data settings show that CurateEvo consistently outperforms prior curation methods, improving average scores by 3.2 and 2.7 points, respectively. Further analyses demonstrate that CurateEvo is compatible with different post-training recipes and substantially reduces curation overhead.