q-bio.NCMar 15, 2026

D-MEM: Dopamine-Gated Agentic Memory via Reward Prediction Error Routing

Authors: Yuru Song, Qi Xin

Organizations: UC San Diego · Carnegie Mellon University

Abstract

Autonomous LLM agents require structured long-term memory, yet current "append-and-evolve" systems like A-MEM face O(N^2) write-latency and excessive token costs. We introduce D-MEM (Dopamine-Gated Agentic Memory), a biologically inspired architecture that decouples short-term interaction from cognitive restructuring via a Fast/Slow routing system based on Reward Prediction Error (RPE). A lightweight Critic Router evaluates stimuli for Surprise and Utility. Routine, low-RPE inputs are bypassed or cached in an O(1) fast-access buffer. Conversely, high-RPE inputs, such as factual contradictions or preference shifts, trigger a "dopamine" signal, activating the O(N) memory evolution pipeline to reshape the agent's knowledge graph. To evaluate performance under realistic conditions, we introduce the LoCoMo-Noise benchmark, which injects controlled conversational noise into long-term sessions. Evaluations demonstrate that D-MEM reduces token consumption by over 80%, eliminates O(N^2) bottlenecks, and outperforms baselines in multi-hop reasoning and adversarial resilience. By selectively gating cognitive restructuring, D-MEM provides a scalable, cost-efficient foundation for lifelong agentic memory.

Figures & tables

Appendix figures & tables4 assets

Supplementary material from the paper’s appendix.

Appendix

Explore similar work

Mar 19, 2026

D-Mem: A Dual-Process Memory System for LLM Agents

Driven by the development of persistent, self-adapting autonomous agents, equipping these systems with high-fidelity memory access for long-horizon reasoning has emerged as a critical requirement. However, prevalent retrieval-based memory frameworks often follow an incremental processing paradigm that continuously extracts and updates conversational memories into vector databases, relying on semantic retrieval when queried. While this approach is fast, it inherently relies on lossy abstraction, frequently missing contextually critical information and struggling to resolve queries that rely on fine-grained contextual understanding. To address this, we introduce D-Mem, a dual-process memory system. It retains lightweight vector retrieval for routine queries while establishing an exhaustive Full Deliberation module as a high-fidelity fallback. To achieve cognitive economy without sacrificing accuracy, D-Mem employs a Multi-dimensional Quality Gating policy to dynamically bridge these two processes. Experiments on the LoCoMo and RealTalk benchmarks using GPT-4o-mini and Qwen3-235B-Instruct demonstrate the efficacy of our approach. Notably, our Multi-dimensional Quality Gating policy achieves an F1 score of 53.5 on LoCoMo with GPT-4o-mini. This outperforms our static retrieval baseline, Mem0∗^\ast (51.2), and recovers 96.7% of the Full Deliberation's performance (55.3), while incurring significantly lower computational costs.
Oct 1, 2026

MemFit: Efficient Long-Term Agentic Memory

Long-term memory systems for large language models (LLMs) have gained popularity for extending reasoning capabilities across applications. Current memory systems rely on LLM agents to organize and consolidate memory, resulting in costly, inefficient write operations. To address this limitation, we propose MemFit, a long-term memory system for conversational agents that reduces the cost and latency of memory operations. Unlike existing systems that rely on expensive LLM calls for memory construction or discard surface-level details through compression, MemFit stores each turn verbatim in an append-only store with near-instantaneous, LLM-free insertion, indexing turns with segment summaries rather than replacing them. Additionally, MemFit uses an LLM-free, multi-path retrieval strategy that combines lexical and semantic signals with cross-encoder reranking over caption- augmented episodes in both textual and multimodal settings. Empirical results on three widely used benchmarks, LoCoMo, MemGallery, and LongMemEval-S, show that MemFit achieves state-of-the-art performance while reducing memory construction time and cost several-fold, providing a scalable and efficient solution for persistent agentic memory.
Aug 4, 2026

LeanMem: Simple and Efficient Long-Term Memory for LLM Agents

Long-term memory is essential for LLM-based agents to sustain interactions and reliably leverage distant history. However, existing memory systems typically process heterogeneous dialogue content through a uniform summarization and retrieval pipeline, leading to either excessive token consumption or irreversible loss of fine-grained evidence. We argue that historical dialogue content should be handled differently according to its compressibility, temporal dynamics, and fidelity requirements. Based on this insight, we propose LeanMem, a lightweight long-term memory framework. LeanMem first filters out low-value content, then stores informative segments as compact profile memory, temporally structured event memory, or source-grounded record memory, depending on the nature of the information. During maintenance, only dynamically evolving event memories are selectively updated, avoiding redundant consolidation of stable profiles and immutable records. During inference, LeanMem dynamically selects memory types and allocates retrieval budgets according to query-specific evidence demands, assembling relevant evidence on demand. On LoCoMo and LongMemEval-S with GPT-4.1-mini and Qwen3-8B, LeanMem improves accuracy over the strongest memory-based baseline in every setting, by up to 15.1 points, at the lowest or near-lowest construction cost, inference tokens, and latency. The code and datasets are included in the supplementary materials.