Trust the Unreliability: Inward Backward Dynamic Unreliability Driven Coreset Selection for Medical Image Classification

The rapid growth of image data has produced large-scale datasets, raising concerns about the time and memory costs of model training. Selecting representative training subsets, however, remains challenging: individual sample contributions are unclear, and model behavior varies across datasets and runs. We address these challenges with a framework that combines coreset selection with an ensemble aggregation over multiple runs. For coreset selection, we propose SCOre-Stratified Selection (SCOSS), which partitions the training data into intervals based on a chosen score and samples from each interval. The ensemble combines predictions from multiple runs, each performed on an independently sampled training subset. As baselines, we use moderate and random selection, each in original and class-balanced versions. We assess the framework with Simple Graph Convolution (SGC) and Support Vector Machine (SVM) classifiers under different sampling ratios. Experiments show that SCOSS is competitive with baselines, often the best choice for SGC, and enables favorable trade-offs between accuracy and efficiency. On the fine-grained dataset, SGC with SCOSS outperforms SVMs when using fewer labeled samples. The code and supplementary materials are publicly available at http://scoss.lucasvalem.com.

Medical image segmentation supports clinical workflows by precisely delineating anatomical structures and lesions. However, medical image datasets medical image datasets suffer from acquisition noise and annotation ambiguity, causing pervasive data uncertainty that substantially undermines model robustness. Existing research focuses primarily on model architectural improvements and predictive reliability estimation, while systematic exploration of the intrinsic data uncertainty remains insufficient. To address this gap, this work proposes leveraging the universal representation capabilities of visual foundation models to estimate inherent data uncertainty. Specifically, we analyze the feature diversity of the model's decoded representations and quantify their singular value energy to define the semantic perception scale for each class, thereby measuring sample difficulty and aleatoric uncertainty. Based on this foundation, we design two uncertainty-driven application strategies: (1) the aleatoric uncertainty-aware data filtering mechanism to eliminate potentially noisy samples and enhance model learning quality; (2) the dynamic uncertainty-aware optimization strategy that adaptively adjusts class-specific loss weights during training based on the semantic perception scale, combined with a label denoising mechanism to improve training stability. Experimental results on five public datasets encompassing CT and MRI modalities and involving multi-organ and tumor segmentation tasks demonstrate that our method achieves significant and robust performance improvements across various mainstream network architectures, revealing the broad application potential of aleatoric uncertainty in medical image understanding and segmentation tasks.

Medical imaging datasets are often characterized by extreme class imbalances, where rare pathologies are significantly underrepresented compared to common conditions. This imbalance poses a dual challenge for Open-Set Recognition (OSR): models must maintain high classification accuracy on known classes while reliably rejecting unknown samples unseen during training in the clinical settings. While recently proposed Deep Simplex Classifier (DSC)\cite{cevikalp2024reaching} and UnCertainty-aware Deep Simplex Classifier (UCDSC)\cite{Aditya_2026_WACV} successfully leverage Neural Collapse to ensure maximal inter-class separation, they rely on a uniform margin that does not account for the varying densities of medical classes. In this paper, we propose DMDSC an enhanced framework featuring a dynamic margin approach. Our approach automatically adapts class-specific margins based on label frequency, enforcing a higher penalty and tighter feature clustering for rare pathologies to counteract the effects of data imbalance. Extensive experiments conducted on diverse medical benchmarks on BloodMNIST\cite{medmnistv2}, OCTMNIST\cite{medmnistv2}, DermaMNIST\cite{medmnistv2}, and BreaKHis~\cite{spanhol2015dataset} datasets, demonstrate that our framework outperforms state-of-the-art methods.