quant-phMar 28, 2026

From Foundation ECG Models to NISQ Learners: Distilling ECGFounder into a VQC Student

Authors: Giovanni dos Santos Franco, Felipe Mahlow, Ellison Fernando Cardoso, Felipe Fanchini

Organizations: Faculty of Sciences, S˜ao Paulo State University (Unesp), Bauru, Brazil. · Hospital Israelita Albert Einstein, S˜ao Paulo, Brazil. · Laboratory of Magnetic Resonance in Neuroradiology (LIM-44), University of S˜ao Paulo Faculty of Medicine Clinics Hospital, S˜ao Paulo, Brazil.

Abstract

Foundation models have recently improved electrocardiogram (ECG) representation learning, but their deployment can be limited by computational cost and latency constraints. In this work, we fine-tune ECGFounder as a high-capacity teacher for binary ECG classification on PTB-XL and the MIT-BIH Arrhythmia Database, and investigate whether knowledge distillation can transfer its predictive behavior to compact students. We evaluate two classical 1D students (ResNet-1D and a lightweight CNN-1D) and a quantum-ready pipeline that combines a convolutional autoencoder, which compresses 256-sample ECG windows into a low-dimensional latent representation, with a 6-qubit variational quantum circuit implemented in Qiskit and executed in a simulated backend. Across both datasets, the teacher provides the strongest overall performance, while distillation yields competitive students under a considerable reduction in trainable parameters. We further analyze the sensitivity of student performance to distillation settings, highlighting consistent accuracy--efficiency trade-offs when compressing a foundation ECG model into classical and quantum-ready learners under a unified evaluation protocol.

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