cs.AIApr 1, 2026

Omni-SimpleMem: Autoresearch-Guided Discovery of Lifelong Multimodal Agent Memory

Authors: Jiaqi Liu, Zipeng Ling, Shi Qiu, Yanqing Liu, Siwei Han, Peng Xia, Haoqin Tu, Zeyu Zheng, 

Organizations: UNC-Chapel Hill · University of Pennsylvania · University of California, Santa Cruz · University of California Berkeley · 

Abstract

AI agents increasingly operate over extended time horizons, yet their ability to retain, organize, and recall multimodal experiences remains a critical bottleneck. Building effective lifelong memory requires navigating a vast design space spanning architecture, retrieval strategies, prompt engineering, and data pipelines; this space is too large and interconnected for manual exploration or traditional AutoML to explore effectively. We deploy an autonomous research pipeline to discover Omni-SimpleMem, a unified multimodal memory framework for lifelong AI agents. Starting from a naïve baseline (F1=0.117 on LoCoMo), the pipeline autonomously executes ∼50{\sim}50 experiments across two benchmarks, diagnosing failure modes, proposing architectural modifications, and repairing data pipeline bugs, all without human intervention in the inner loop. The resulting system achieves state-of-the-art on both benchmarks, improving F1 by +411% on LoCoMo (0.117→\to0.598) and +214% on Mem-Gallery (0.254→\to0.797) relative to the initial configurations. Critically, the most impactful discoveries are not hyperparameter adjustments: bug fixes (+175%), architectural changes (+44%), and prompt engineering (+188% on specific categories) each individually exceed the cumulative contribution of all hyperparameter tuning, demonstrating capabilities fundamentally beyond the reach of traditional AutoML. We provide a taxonomy of six discovery types and identify four properties that make multimodal memory particularly suited for autoresearch, offering guidance for applying autonomous research pipelines to other AI system domains. Code is available at this https://github.com/aiming-lab/SimpleMem.

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