When Modalities Remember: Continual Learning for Multimodal Knowledge Graphs

Biomedical knowledge graphs are increasingly large, dynamic, and multimodal, driven by rapid advances in biotechnology such as high-throughput sequencing. Machine learning models can infer previously unobserved biomedical relationships and characterize biomedical entities in these graphs, but existing knowledge graph embedding methods and their continual learning extensions either assume static graph structure or fail to exploit multimodal information under evolving data distributions. They also apply uniform regularization across all model parameters, ignoring that different modalities may exhibit distinct forgetting dynamics as the graph evolves. We propose the Continual Multimodal Knowledge Graph Learner (CMKL), a CL framework for biomedical KGs that natively encodes structure, text, and molecules, fuses them through a Mixture-of-Experts (MoE) router, and protects previously learned knowledge with standard EWC regularization and a K-means-diverse multimodal replay buffer. We evaluate CMKL on a 129K-entity biomedical continual benchmark with 10 tasks. On continual biomedical entity classification, CMKL reaches AP 0.591 versus 0.370 for the strongest structural baseline, a 60% gain that is driven by access to multimodal features and preserved across the sequence with near-zero forgetting (AF 0.008). On continual relationship prediction, CMKL reaches AP $0.062$, matching Naive Sequential and EWC (0.058) within seed noise and outperforming Joint Training (0.047, p=0.045) and LKGE (0.039). A frozen-text ablation reaches AP 0.136, more than double any jointly trained model, yet that signal is unreachable by margin-ranking gradients: the greedy-modality asymmetry lives at the representation level, not the fusion level, and MoE routing manages it by suppressing the unreachable modality without forcing it through a learned bottleneck. Code: github.com/yradwan147/cmkl-neurips2026

Multimodal knowledge graphs (MMKGs) organize information across different modalities to support multimodal Graph Retrieval-Augmented Generation (RAG), which aims to improve the performance of multimodal large language models (MLLMs). The effectiveness of these multimodal Graph RAG methods largely depends on the quality of the constructed MMKGs. However, most existing methods construct MMKGs without explicit guidance on graph quality, while reinforcement learning (RL)-based methods that rely on final-answer correctness may provide only indirect feedback on MMKG quality. To address these limitations, we propose MMKG-R1, a novel MMKG-quality-driven RL framework for training an MLLM as a multimodal knowledge constructor. To be specific, MMKG-R1 introduces multiple quality-aware rewards to directly evaluate both the quality of information extracted from individual knowledge sources and the quality of the assembled MMKG. These rewards are then used to guide the RL training. Experiments across multiple datasets show that MMKG-R1 constructs MMKGs that improve downstream question-answering accuracy.

Real-world multimodal knowledge graphs (MKGs) are inherently heterogeneous, modeling entities that are associated with diverse modalities. Traditional knowledge graph embedding (KGE) methods excel at learning continuous representations of entities and relations, yet they are typically designed for unimodal settings. Recent approaches extend KGE to multimodal settings but remain constrained, often processing modalities in isolation, resulting in weak cross-modal alignment, and relying on simplistic assumptions such as uniform modality availability across entities. Vision-Language Models (VLMs) offer a powerful way to align diverse modalities within a shared embedding space. We propose Vision-Language Knowledge Graph Embeddings (VL-KGE), a framework that integrates cross-modal alignment from VLMs with structured relational modeling to learn unified multimodal representations of knowledge graphs. Experiments on WN9-IMG and two novel fine art MKGs, WikiArt-MKG-v1 and WikiArt-MKG-v2, demonstrate that VL-KGE consistently improves over traditional unimodal and multimodal KGE methods in link prediction tasks. Our results highlight the value of VLMs for multimodal KGE, enabling more robust and structured reasoning over large-scale heterogeneous knowledge graphs.