cs.LGApr 13, 2026

Can AI Detect Life? Lessons from Artificial Life

Authors: Ankit GuptaChristoph Adami

Organizations: Michigan State University · Department of Computer Science and Engineering 2Program in Evolution, Ecology, and Behavior 3 Department of Microbiology, Genetics, and Immunology 4 Department of Physics and Astronomy Michigan State University, East Lansing, MI

Abstract

Modern machine learning methods have been proposed to detect life in extraterrestrial samples, drawing on their ability to distinguish biotic from abiotic samples based on training models using natural and synthetic organic molecular mixtures. Here we show using Artificial Life that such methods are easily fooled into detecting life with near 100% confidence even if the analyzed sample is not capable of life. This is due to modern machine learning methods' propensity to be easily fooled by out-of-distribution samples. Because extra-terrestrial samples are very likely out of the distribution provided by terrestrial biotic and abiotic samples, using AI methods for life detection is likely to yield significant false positives.

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