Trustworthy Endoscopic Super-Resolution

Super-resolution can make inspection images appear sharper without preserving the evidence needed to detect a defect. We study this failure mode with a benchmark that separates reconstruction from detection and evaluates both at a predeclared low false-positive rate. Ten end-to-end repetitions combine independently generated line/space and contact-hole images with model training, calibration, clean controls, weak defects, and a held-out defect morphology. Every reconstruction is scored by the same local residual detector, while direct and jointly trained detectors form a separate comparison track. Reconstruction fidelity and inspection utility diverge: the two learned reconstruction models attain the highest structural similarity yet detect fewer defect pixels than bicubic interpolation in every paired repetition. A direct DeepLabV3 detector reaches $0.1984\pm0.0385$ recall at $0.000174\pm0.000084$ false-positive rate and satisfies the held-out feasibility criterion in all ten repetitions. An illustrative joint model, DPU-WaferSR, passes independent clean calibration but exceeds the held-out limit in all ten repetitions, demonstrating that calibration success does not guarantee transfer. Weak-defect recall remains near zero for every feasible method. Applying the unchanged policies to 4,591 public Carinthia-S masks further reveals large method-dependent shifts on real SEM texture. These results support a simple conclusion: super-resolution for inspection should be judged by preserved task evidence and operating-point transfer, not reconstruction quality alone.

The widespread adoption of machine learning in critical applications demands techniques to mitigate high-consequence errors. Our method utilizes a dual-classifier GBDT pipeline to distinguish routine human-like errors from high-risk non-human misclassifications. Evaluated across three domains, animal breed classification, skin lesion diagnosis (ISIC 2018), and prostate histopathology (SICAPv2), our framework demonstrates robust safety improvements. To address real-world deployment concerns, our results confirm the pipeline introduces negligible inference latency (1.60% overhead for the animal dataset, 1.84% for ISIC, and 1.70% for SICAPv2) while outperforming traditional Maximum Class Probability (MCP) baselines in correction precision. Our conservative correction strategy successfully reduced dangerous non-human errors by 34.1% in ISIC and 12.57% in SICAPv2, improving super-class diagnostic safety to 90.41% and 92.13% respectively. This proves that safety-critical reliability can be substantially enhanced post-hoc without expensive model retraining. keywords: Error Analysis, Post-hoc Correction, Trustworthy AI.

Medical image super-resolution (MedSR) is essential for improving diagnostic precision across diverse imaging modalities such as MRI, CT, X-ray, Ultrasound, and Fundus imaging. Despite rapid advances in deep learning, challenges remain in preserving anatomical accuracy, maintaining perceptual quality, and generalizing across medical domains. This paper presents MedSR-Vision, a novel unified deep learning framework for evaluating and comparing super-resolution models across five modalities: Brain MRI, Chest X-ray, Renal Ultrasound, Nephrolithiasis CT, and Spine MRI, at magnification scales of $\times2$, $\times3$, and $\times4$. Three representative models namely SRCNN, SwinIR, and Real-ESRGAN are benchmarked using multiple quantitative metrics encompassing fidelity, perceptual realism, and sharpness. Experimental analysis demonstrates that Real-ESRGAN achieves superior perceptual quality and edge recovery at higher scales, SwinIR excels in preserving structural and diagnostic features, and SRCNN provides efficient and stable performance at lower magnifications. The results establish domain-specific insights and practical guidelines for model selection in clinical imaging workflows, offering a standardized evaluation framework for future medical image super-resolution research and deployment.