AnemiaVision: Non-Invasive Anemia Detection via Smartphone Imagery Using EfficientNet-B3 with TrivialAugmentWide, Mixup Augmentation, and Persistent Patient History Management

Neonatal jaundice (hyperbilirubinemia) is one of the most common conditions affecting newborns worldwide, with India alone recording roughly 15 million cases per year. Early detection is critical, yet standard diagnosis requires blood tests that are often impractical in rural clinics where laboratory facilities are limited. This paper presents NeoJaundice-AI, a smartphone-based screening system that uses photographs of a baby's skin and sclera (eye white) to estimate jaundice severity and predict serum bilirubin levels in under three seconds without requiring internet connectivity. The proposed system is built on a dual-branch EfficientNet-B0 architecture that independently processes skin and sclera images. Deep features are fused with handcrafted YCbCr color statistics to jointly perform four-class severity classification and continuous bilirubin regression. A key contribution is a synthetic jaundice generation method that simulates bilirubin-induced yellowing through controlled YCbCr channel modifications on normal neonatal skin images. This approach addresses data scarcity, particularly for severe jaundice cases and darker Indian skin tones (Fitzpatrick Types IV to VI). In addition, a skin-tone normalization module improves prediction consistency across diverse neonatal complexions. Experimental results demonstrate an overall classification accuracy of 91.8 percent, a clinical sensitivity of 93.5 percent, and a bilirubin mean absolute error of 1.4 mg/dL. After INT8 quantization and ONNX conversion, the model size is reduced to 8.3 MB while maintaining inference times below three seconds on standard Android devices. To the best of our knowledge, this is the first India-focused neonatal jaundice AI system that combines multimodal image fusion, skin-tone adaptation, synthetic data augmentation, and fully offline mobile deployment within a single framework.

Deploying AI-based anomaly detection across diverse clinical imaging settings remains challenging because most existing methods rely on modality-specific architectures, anatomical priors, or extensive retraining, limiting their use as general-purpose screening tools. One-class classification (OCC) offers a label-efficient alternative by training exclusively on normal data, but conventional two-stage pipelines fit a density estimator directly on raw pretrained embeddings, leaving substantial discriminative structure in the latent space unexploited. We introduce a training-free, modality-agnostic framework that inserts an explicit manifold-refinement stage between feature extraction and anomaly scoring. Empirical density weights, estimated via a UMAP-derived neighborhood graph, guide an iterative shift of embeddings toward locally dense regions, compacting normal samples, leaving anomalies relatively isolated prior to Gaussian density estimation and Mahalanobis-based scoring. This refinement introduces no additional trainable parameters and no architectural modification, allowing it to be layered onto any pretrained encoder. Evaluated on the MedIAnomaly benchmark across seven datasets spanning five imaging modalities (X-ray, MRI, fundus, dermatoscopy, histopathology), the framework achieves the best AUC on four datasets and the best Average Precision on five datasets among methods evaluated in the benchmark, outperforming specialized reconstruction and diffusion-based methods with a single fixed hyperparameter configuration across all modalities. These results demonstrate that meaningful gains can be achieved through post-hoc geometric refinement of existing representations rather than bespoke encoders, offering a practical and scalable AI screening framework for real-world, multi-modality clinical workflows where retraining and abnormal-case annotation are costly or infeasible.

Retinal blood vessel segmentation plays a vital role in the early detection of diabetic retinopathy and glaucoma. While recent deep learning models have achieved great segmentation accuracy, they typically require heavy computational resources, making real-world deployment on edge devices difficult. In this paper, we propose LightVesselNet, an efficient neural network designed for retinal vessel segmentation in a resource-constrained environment. Despite containing only 75K parameters, LightVesselNet performs competitively with much larger models. The network employs a compact encoder decoder architecture enhanced with channel and spatial attention mechanisms, a multi-scale feature aggregation module at the bottleneck, and a subpixel upsampling strategy in the decoder. A dedicated edge residual connection preserves fine vessel detail throughout decoding. Extensive experiments on five publicly available datasets: DRIVE, STARE, CHASEDB1, FIVES, and HRF, yield sensitivity scores of 0.8189, 0.8499, 0.8640, 0.8634, 0.8096, and Dice coefficients of 0.8070, 0.8072, 0.8181, 0.8649, and 0.7686, respectively. LightVesselNet shows improved efficiency (Performance vs Parameter or GFlops) compared to State-of-the-Art models. Cross-dataset evaluation confirms the model's generalisation capability. Overall, LightVesselNet is a strong candidate for deployment in low-resource clinical settings and mobile screening tools.