Abstract
Quantum computing instructors face a compounding problem: the concepts are counterintuitive, the mathematical formalism is dense, and qualified faculty are scarce outside a small number of well-resourced institutions. Our prior work introduced a knowledge-graph-augmented tutoring prototype with two specialized LLM agents: a Teaching Agent for dynamic interaction and a Lesson Planning Agent for lesson generation. Validated on simulated runs rather than in a real course, that prototype left open whether more aggressive agent specialization would be needed to handle the full range of quantum education tasks under real student load. This paper answers the three questions that the prototype could not answer. Can agent specialization solve the reliability problem in a domain as technically demanding as quantum information science? Can the system run in a real course, not a demonstration? Does the instructor gain actionable intelligence from the deployment? We present ITAS (Intelligent Teaching Assistant System), a multi-agent tutoring system built around four contributions: a five-module QIS curriculum grounded in Watrous's information-first framework, a Spoke-and-Wheel teaching architecture with quantum-specialized agents, a cloud infrastructure designed for production use and regulatory compliance, and a conversational analytics layer for instructors and content developers. Piloted in a quantum computing course at Old Dominion University, the system supports all three answers: deployment evidence is consistent with specialization addressing the task-boundary failures observed in the prototype, cloud infrastructure supports classroom-scale concurrency at sub-textbook cost, and the analytics agent surfaces curriculum gaps the instructor could not otherwise see.
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Apr 27, 2026cs.MA
Large language model tutors are easy to build in a notebook and hard to run in a real course. We describe ITAS (Intelligent Teaching Assistant System), a multi-agent tutoring system that a graduate quantum computing course used for a semester at Old Dominion University. The system has three layers. The teaching layer is a Spoke-and-Wheel of three parallel specialist agents (Video, Code, Guidance) followed by a Synthesizer, plus a separate autograder that evaluates both the correctness and the approach of checkpoint submissions. The operational layer is four Cloud Run microservices with session state in Cloud SQL and interaction events streamed through Pub/Sub to BigQuery. The feedback layer is a narrow-scope conversational agent that answers instructor questions over per-lesson pseudonymized event streams, addressing what we call the Blind Instructor Problem: LLM tutors accumulate more data about students than the instructor can reach through routine channels. The architecture is a direct response to specific failures of an earlier prototype, and we describe which of those fixes carried forward and which were dropped for this iteration. We report on a pilot deployment (five students, one course, one semester) interpreted as system-behavior evidence rather than learning-outcome evidence: the teaching layer handled 334 chat turns without the task-boundary hallucinations that domain consolidation would have risked, the operational layer captured 10,628 events across five modules, and the feedback layer surfaced two findings the instructor acted on mid-semester. We do not claim the pilot generalizes. We do claim that the system as described is one workable answer to the question of what an LLM-based ITS needs to look like end-to-end to run in a real course.
Iizalaarab Elhaimeur, Nikos Chrisochoides
Apr 27, 2026cs.CY
Multi-agent LLM tutoring systems improve response quality through agent specialization, but each student query triggers several concurrent API calls whose latencies compound through a parallel-phase maximum effect that single-agent systems do not face. We instrument ITAS, a four-agent tutoring system built on Gemini 2.5 Flash and Google Vertex AI, across three throughput tiers (Standard PayGo, Priority PayGo, and Provisioned Throughput) and eleven concurrency levels up to 50 simultaneous users, producing over 3,000 requests drawn from a live graduate STEM deployment. Priority PayGo maintains flat sub-4-second response times across the full load range; Standard PayGo degrades substantially under classroom-scale concurrency; and Provisioned Throughput delivers the lowest latency at low concurrency but saturates its reserved capacity above approximately 20 concurrent users. Cost analysis places both pay-per-token tiers well below the price of a STEM textbook per student per semester under a worst-case usage ceiling. Provisioned Throughput, expensive under continuous provisioning, becomes cost-competitive for institutions that can predict and concentrate their traffic toward high utilization. These results provide concrete tier-selection guidance across deployment scales from a single seminar to a university-wide rollout.
Iizalaarab Elhaimeur, Nikos Chrisochoides
Date pendingphysics.chem-ph
Quantum chemistry is a foundational enabling tool for the fields of chemistry, materials science, computational biology and others. Despite of its power, the practical application of quantum chemistry simulations remains in the hands of qualified experts due to methodological complexity, software heterogeneity, and the need for informed interpretation of results. To bridge the accessibility gap for these tools and expand their reach to chemists with broader backgrounds, we introduce El Agente Quntur, a hierarchical, multi-agent AI system designed to operate not merely as an automation tool but as a research collaborator for computational quantum chemistry. Quntur was designed following three main strategies: i) elimination of hard-coded procedural policies in favour of reasoning-driven decisions, ii) construction of general and composable actions that facilitate generalization and efficiency, and iii) implementation of guided deep research to integrate abstract quantum-chemical reasoning across subdisciplines and a detailed understanding of the software's internal logic and syntax. Although instantiated in ORCA, these design principles are applicable to research agents more generally and easily expandable to additional quantum chemistry packages and beyond. Quntur supports the full range of calculations available in ORCA 6.0 and reasons over software documentation and scientific literature to plan, execute, adapt, and analyze in silico chemistry experiments following best practices. We discuss the advances and current bottlenecks in agentic systems operating at the research level in computational chemistry, and outline a roadmap toward a fully autonomous end-to-end computational chemistry research agent.
Juan B. Pérez-Sánchez, Yunheng Zou, Jorge A. Campos-Gonzalez-Angulo +12