cs.AIMay 5, 2026

Quantifying the human visual exposome with vision language models

Authors: Christian RomingerAndreas R. SchwerdtfegerMalay Gaherwar SinghDimitri KhudyakowElizabeth A. M. MichelsFabian WolfJakob Nikolas KatherMagdalena Katharina Wekenborg

Organizations: University of Graz · Health Psychology, University of Graz, Graz, Austria · TU Dresden · Else Kröner Fresenius Center for Digital Health, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany · University Hospital Carl Gustav Carus Dresden · National Center for Tumor Diseases Heidelberg · Department of Medicine I, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany · Medical Oncology, National Center for Tumor Diseases (NCT), University Hospital Heidelberg, Heidelberg, Germany

Abstract

The visual environment is a fundamental yet unquantified determinant of mental health. While the concept of the environmental exposome is well established, current methods rely on coarse geospatial proxies or biased self reports, failing to capture the first person visual context of daily life. We addressed this gap by coupling ecological momentary assessment with vision language models (VLMs) to quantify the semantic richness of human visual experience. Across 2674 participant generated photographs, VLM derived estimates of greenness robustly predicted momentary affect and chronic stress, consistent with established benchmarks. We then developed a semi autonomous large language model (LLM) based pipeline that mined over seven million scientific publications to extract nearly 1000 environmental features empirically linked to mental health. When applied to real world imagery, up to 33 percent of VLM extracted context ratings significantly correlated with affect and stress. These findings establish a scalable objective paradigm for visual exposomics, enabling high throughput decoding of how the visible world is associated with mental health.

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