MHGraphBench: Knowledge Graph-Grounded Benchmarking of Mental Health Knowledge in Large Language Models
Authors: Weixin Liu, Congning Ni, Shelagh A. Mulvaney, Susannah L. Rose, Murat Kantarcioglu, Bradley A. Malin, Zhijun Yin
Organizations: Vanderbilt University, Nashville, TN, USA · Vanderbilt University Medical Center, Nashville, TN, USA · Virginia Tech, Blacksburg, VA, USA
Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we present a knowledge-graph (KG)-grounded benchmark for assessing LLMs on mental-health entity recognition, relation judgment, and two-hop reasoning. The benchmark is derived from PrimeKG and comprises nine task families with KG-supported answers and controlled negative options. Experiments across 15 closed- and open-source LLMs reveal a persistent recognition-to-judgment gap: leading models achieve near-ceiling performance on entity typing and on the small relation-typing subset, yet they still struggle with relation prediction and two-hop reasoning. Additionally, short KG-derived snippets benefit some models but degrade performance for others. Moreover, output-format reliability can substantially influence measured performance under constrained multiple-choice settings, highlighting the critical role of response validity in benchmark-based evaluation. MHGraphBench should therefore be interpreted as evaluating agreement with a curated mental-health slice of PrimeKG under a constrained multiple-choice interface, rather than as a direct assessment of real-world clinical safety.
A recent Nature Medicine study reports that general-purpose frontier LLMs outperform specialized retrieval-augmented clinical tools on medical benchmarks, and that retrieval can hurt strong models. We ask the natural follow-up: does structured knowledge-graph (KG) grounding change this, and when does grounding help at all? We contribute two results. First, a reproduction: the study's headline HealthBench score (~88) is the Consensus variant, not full HealthBench, where frontier models and ideal completions both score ~46-47 under a physician-calibrated grader (agreement 82.5%); we reproduce GPT-5.2 Consensus =90.9 and flag a score-deflating grader bug. Second, a knowledge-boundary result. Using a graph+vector engine (samyama-graph) over the public biomedical KG PrimeKG, neither naive triple retrieval nor an agentic natural-language-to-Cypher loop (82% successful queries) improves MedQA across a weak-to-strong model ladder (all |Delta| <= 3.4). On a synthetic counterfactual KG, and on a hybrid benchmark mixing known and novel facts, the identical pipeline lifts out-of-training accuracy from chance to ~100% (+68 to +79) while adding nothing on known facts (a no-LLM arm answers both). Across three regimes (no-knowledge, graph-aided, hybrid), grounding helps only insofar as the decisive fact lies outside the model's training -- public-KG facts are redundant, private and novel data are where it pays -- matching the study's institutional-data caveat.
People increasingly use large language models (LLMs) for mental health support, yet their safety in evolving, high-risk conversations remains poorly characterised. We developed K-Bench, a clinician-calibrated, protected benchmark evaluating 125 model configurations representing 33 base models from 14 providers across a fixed cohort of 200 multi-turn vignettes involving suicide, self-harm, domestic violence, substance misuse, and no-risk presentations. Synthetic patient conversations showed substantial distributional overlap with real human-AI conversations. A frozen GPT-4o judge achieved 94.2% exact agreement with clinician consensus across 6,751 eligible item comparisons from 151 clinician-rated transcripts. Leading models combined strong supportive conversation with combined-risk scores above 95, whereas risk exploration exposed substantial variation among lower-performing configurations. Therapeutic prompting produced configuration-specific gains concentrated among weaker models, while elevated reasoning produced no average improvement. K-Bench combines broader clinical coverage and configuration-scale comparison with a continuously updated public leaderboard whose operational test materials are protected from direct optimisation. The leaderboard is available at www.k-bench.ai.
Laura M. Vowels, Matthew J. Vowels, Shivali Sharma +9
Graph reasoning provides a promising testbed for evaluating the reasoning ability of large language models (LLMs), as graph instances can be programmatically generated, structurally controlled, and naturally scaled to long-input settings. However, existing graph reasoning benchmarks have limited coverage of data complexity, rely heavily on manual construction, and lack unified evaluation across text-based and code-based reasoning modes. To address these limitations, we propose {\dataset}, a five-stage \textit{semi-automatic} framework for constructing complex graph reasoning benchmarks. It expands benchmark coverage along five dimensions: \textit{Graph Size}, \textit{Task Complexity}, \textit{Task Description}, \textit{Graph Loading}, and \textit{Task Source}. The framework uses an LLM-based data generator to automatically produce task descriptions, graph data, reference solutions, graph-loading scripts, question forms, and evaluation scripts, while retaining human validation at key quality-control stages. Based on it, we construct a benchmark with 202 tasks and evaluate LLMs under text-based, code-based, and augmented reasoning settings. Experiments show that the complexity dimensions reveal model limitations that are less visible in existing benchmarks; existing fine-tuned models struggle to generalize to GraphGym, whereas retrieval-augmented methods show scenario-dependent adaptability, improving textual reasoning but not consistently improving coding reasoning. These findings suggest that ours serves as a challenging and diagnostic benchmark for graph reasoning and provides empirical guidance for future enhancement methods. Code and dataset will be published soon.