SIREM: Speech-Informed MRI Reconstruction with Learned Sampling
Authors: Md Hasan, Nyvenn Castro, Daiqi Liu, Lukas Mulzer, Jana Hutter, Jonghye Woo, Moritz Zaiss, Andreas Maier, +1 more
Organizations: 1Pattern Recognition Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany · Institute of Radiology, University Hospital Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany · 3Institut für Informationsverarbeitung, Leibniz Universität Hannover, Hannover, Germany · Department of Radiology, Harvard Medical School and Massachusetts General Hospital, Boston, MA, USA
Abstract
Real-time magnetic resonance imaging (rtMRI) of speech production enables non-invasive visualization of dynamic vocal-tract motion and is valuable for speech science and clinical assessment. However, rtMRI is fundamentally constrained by trade-offs among spatial resolution, temporal resolution, and acquisition speed, often leading to undersampled k-space measurements and degraded reconstructions. We propose SIREM, a speech-informed MRI reconstruction framework that uses synchronized speech as a cross-modal prior. The central idea is that vocal-tract configurations during speech are correlated with the produced acoustics, making part of the image content predictable from audio. SIREM models each frame as a fusion of an audio-driven component and an MRI-driven component through a spatial weighting map. The audio branch predicts articulator-related structure from speech, while the MRI branch reconstructs complementary content from measured k-space data. We further introduce a learnable soft weighting profile over spiral arms, enabling a differentiable study of how k-space arm usage interacts with speech-informed fusion. This yields a unified multimodal formulation that combines audio-driven prediction, MRI reconstruction, and sampling adaptation. We evaluate SIREM on the USC speech rtMRI benchmark against standard baselines, including gridding, wavelet-based compressed sensing, and total variation. SIREM introduces a speech-informed reconstruction paradigm that operates in a substantially higher-throughput regime than iterative methods while preserving anatomically plausible vocal-tract structure. These results establish an initial benchmark for multimodal speech-informed rtMRI reconstruction and highlight the potential of synchronized speech as an auxiliary prior for fast reconstruction. The source code is available at https://github.com/mdhasanai/SIREM
Segmenting vocal tract articulators in real-time MRI (rtMRI) is a challenging dynamic image segmentation problem characterized by low contrast, rapid motion, and limited spatial resolution. However, while rtMRI acquisitions may provide synchronized acoustic signals, existing methods discard this information, and the few multimodal approaches that incorporate audio cannot be deployed when audio is unavailable. We propose a three-stage framework that leverages acoustic and phonological supervision during training while requiring only the rtMRI image at inference: phonological representations are converted into spatial bounding-box priors for articulator localization, visual and acoustic encoders are aligned via dual-level cross-modal contrastive pretraining, and the learned representations are fused through a cross-attention decoder, effectively transferring multimodal knowledge into a single-modality inference pipeline. Evaluated on 75-Speaker~Annot-16 and USC-TIMIT datasets, our method outperforms existing unimodal and multimodal methods, demonstrating that multimodal supervision provides transferable benefits for precise and clinically deployable vocal tract segmentation.
Real-time MRI (rtMRI) captures the dynamics of the entire vocal tract during speech, but labeled data are scarce and the modality - single-slice, grayscale, low-resolution - differs substantially from the natural videos that video foundation models are trained on. We introduce Arti-JEPA, a joint embedding predictive architecture to model vocal tract rtMRI by continuing its self-supervised objective on about 62h of unlabelled vocal-tract videos, and evaluate the frozen representation on three tasks: cross-domain phoneme prediction (on typical speakers), fluent-vs-disfluent classification (a corpus containing stuttered speech), and characterizing pre/post-operative transfer (after partial glossectomy). Three key findings emerge. (1) A temporal video prior decisively outperforms per-frame image encoders, and latent prediction (V-JEPA) is at least as strong as pixel reconstruction (VideoMAE), with the edge on fine-grained phonemes. (2) Domain adaptation is \emph{task-dependent}: it roughly doubles cross-domain phoneme prediction κ (to 0.352) but does not help binary stuttering classification. (3) Arti-JEPA was able to recover phoneme signal from pre/post glossectomy speech --- an in-domain probe decodes patients at least as well as a typical speaker, indicating that the residual transfer gap is cross-speaker/domain misalignment, not surgical signal loss, and post-operative decoding does not fall below performance on pre-operative speech. Together, these position a frozen, domain-adapted rtMRI encoder as a reusable measurement tool for articulatory and clinical speech science.
Speech production is a complex process spanning neural planning, motor control, muscle activation, and articulatory kinematics. While the acoustic speech signal is the most accessible product of the speech production act, it does not directly reveal its causal neurophysiological substrates. We present the first simultaneous acquisition of real-time (dynamic) MRI, EEG, and surface EMG, capturing several key aspects of the speech production chain: brain signals, muscle activations, and articulatory movements. This multimodal acquisition paradigm presents substantial technical challenges, including MRI-induced electromagnetic interference and myogenic artifacts. To mitigate these, we introduce an artifact suppression pipeline tailored to this tri-modal setting. Once fully developed, this framework is poised to offer an unprecedented window into speech neuroscience and insights leading to brain-computer interface advances. The source code and data are available.