Latent World Recovery for Multimodal Learning with Missing Modalities
Authors: Hui Wang, Tianyu Ren, Joseph Butler, Christopher Baker, Karen Rafferty, Simon McDade
Abstract
We study multimodal learning under missing modalities, with particular motivation from bioscience applications in which heterogeneous modalities are often only partially available when decisions need to be made. We propose Latent World Recovery (LWR), a framework built on two key ideas: (i) modality-specific embeddings from different modalities are aligned in a shared latent space, and (ii) a unified representation is constructed by fusing only the embeddings of the modalities that are actually available at both training and inference time. Rather than imputing missing modalities or requiring a fixed modality set, LWR treats each modality as a partial perception of an underlying latent state and performs availability-aware representation learning directly from the observed modalities. This combination of neighbor-based latent alignment and availability-aware modality fusion enables robust multimodal prediction under partial observation, while avoiding error propagation from explicit reconstruction of missing modalities. We evaluate the proposed framework on real-world incomplete multi-omics benchmarks and demonstrate that it provides an effective approach to downstream tasks such as cancer phenotype classification and survival prediction.
This paper addresses the missing-modality challenge in multi-modal learning by introducing Unsupervised Learning for Missing Modalities in Multi-Modal Learning (UL4M4), a flexible framework that imputes missing feature embeddings in a task-independent manner before supervised prediction. We propose modality-specific normalization and a novel partial-modality distance metric to enable fair clustering of incomplete observations, capturing cross-modal structures while preserving scale-invariance across varying dimensionalities and modality counts. Cluster centers from this unsupervised stage guide an iterative greedy imputation process for any missing modalities during training or inference, supporting arbitrary numbers of modalities and arbitrary missing patterns per sample. The imputation module is lightweight, uses frozen encoders, and decouples from the downstream task, allowing easy integration with any fusion/prediction architecture. Extensive experiments under diverse and highly incomplete regimes demonstrate UL4M4's robustness, achieving, to the best of our knowledge, the first consistent F1-Micro scores above 0.7 on challenging missing configurations even when more than 50% of modality slots are missing. Results are also stable across cluster sizes and significantly outperform state-of-the-art baselines. Code is available here: https://github.com/h-ismkhan/Multimodal-Learning-with-Missing-Modalities-via-Unsupervised-Learning.
Real-world multimodal learning is often hindered by missing modalities. While Incomplete Multimodal Learning (IML) has gained traction, existing methods typically rely on the unrealistic assumption of full-modal availability during training to provide reconstruction supervision or cross-modal priors. This paper tackles the more challenging setting of IML under training-time incomplete observations, which precludes reliance on a ``God's eye view'' of complete data. We propose LIMSSR (LLM-Driven Incomplete Multimodal Sequence-to-Score Reasoning), a framework that reformulates this challenge as a conditional sequence reasoning task. LIMSSR leverages the semantic reasoning capabilities of Large Language Models via Prompt-Guided Context-Aware Modality Imputation and Multidimensional Representation Fusion to infer latent semantics from available contexts without direct reconstruction. To mitigate hallucinations, we introduce a Mask-Aware Dual-Path Aggregation to dynamically calibrate inference uncertainty. Extensive experiments on three Action Quality Assessment datasets demonstrate that LIMSSR significantly outperforms state-of-the-art baselines without relying on complete training data, establishing a new paradigm for data-efficient multimodal learning. Code is available at https://github.com/XuHuangbiao/LIMSSR.
Multi-modal classification leverages complementary information across diverse data sources to enhance predictive performance. However, real-world scenarios subject to operational constraints, such as sensor failures or privacy restrictions, lead to inconsistent modality availability between training and inference times. To handle missing modalities, prior studies have mainly covered bimodal data setups and focused on designing robust fusion processes. Instead, we adopt a multi-modal co-learning framework that prioritizes inter-modal collaboration rather than multi-modal fusion. Specifically, we consider that any subset of modalities may be absent, without assuming predefined missing-modality patterns, an inference scenario we refer to as missing arbitrary modalities. To address this challenge, we introduce two alternative approaches that leverage information at both feature- and decision-level. Experiments on two multi-modal classification benchmarks demonstrate significant robustness gains in various missing modality conditions. The first method shows more robust behavior under minimal missing conditions, where a single modality is absent, whereas the second performs better under extreme missing conditions, where all-but-one modalities are missing. Our code is available at https://github.com/fmenat/Co4Miss.
Francisco Mena, Dino Ienco, Roberto Interdonato +2