Organizations: Department of Computer Science, Quaid-e-Awam University of Engineering, Sciences & Technology, Paksitan · Department of Artificial Intelligence, Quaid-e-Awam University of Engineering, Sciences & Technology, Pakistan · The Faculty of Artificial Intelligence and Cyber Security, Universiti Teknikal Malaysia Melaka · Department of Data Science, Quaid-e-Awam University of Engineering, Sciences & Technology, Pakistan · Department of Computer Science and Digital Technologies, School of Architecture, Computing and Engineering, University of East London
Abstract
Despite recent advancements in deep learning, accurately classifying brain tumors from MRI images continues to pose challenges. In this research, we present a comprehensive evaluation of five different convolutional neural networks (CNN) architectures, including a customized baseline model and four pre-trained models - for use in classifying multi-class brain tumors using a clinically-sourced dataset of approximately 10,000 MRI images. We have utilized five different architectures; VGG16, VGG19, DenseNet121, and EfficientNetB0, which were all tested and trained within an identical experimental framework. Performance was measured by both overall accuracy and tumor-wise recall as a means to measure the clinically-relevant performance of each architecture. We found that EfficientNetB0 had the best overall classification accuracy at 95%, when compared to the other architectures tested; specifically VGG16 (94.37%), VGG19 (92.29%), DenseNet121 (90.91%) and the customized CNN (78.00%). An especially important finding of our research was the considerable improvement in detecting meningiomas; specifically, while simple CNNs could detect meningiomas with a recall rate of approximately 20%, EfficientNetB0 was able to detect meningiomas with a recall rate of 89%. Meningiomas are often difficult to detect because they can appear very subtly on MRI images. Additionally, an interesting finding was that the deeper VGG19 performed worse than the shallower VGG16. This indicates that in many cases the architectural efficiency of a CNN model may be more important than its depth when working with medical images. Overall, EfficientNetB0 appears to provide the optimal trade-off between classification accuracy, number of parameters used in the model and clinically meaningful performance.
Improving patient outcomes depends on the prompt and accurate diagnosis of brain tumors, but manual MRI scan analysis is still time-consuming and unreliable. Although deep learning has shown promise, many of the models that are now in use are computationally intensive and have difficulty handling the intrinsic complexity and variety of different types of brain tumors. In this work, we propose a lightweight yet high-performing Convolutional Neural Network (CNN) for multi-class brain tumor classification, employing MRI images to target gliomas, meningiomas, pituitary tumors, and healthy (no tumor) instances. The model was rigorously evaluated on two publicly accessible datasets from Figshare and Kaggle. Leveraging efficient feature extraction and optimized training strategies, our CNN achieved classification accuracies of 99.03% and 99.28%, along with ROC scores of 99.88% and 99.94% on Dataset 1 and Dataset 2, respectively-all while utilizing significantly fewer parameters than popular pre-trained architectures. In contrast to cutting-edge models like DenseNet201, MobileNetV2, VGG19, Xception, InceptionV3, and ResNet50, our approach consistently demonstrated superior performance with reduced computational overhead. These findings highlight the potential of the proposed model as a practical and reliable diagnostic aid in clinical environments.
Deep learning has shown significant potential in medical image analysis, particularly for disease detection using MRI scans. Accurate and early diagnosis of brain tumors remains challenging due to the complexity of brain structures and reliance on manual interpretation. This work presents an automated deep learning-based approach for brain tumor detection from MRI images using Convolutional Neural Networks and Residual Networks. Transfer learning is applied with two pretrained architectures, ResNet18 and ResNet50, to classify MRI scans into tumor and non-tumor categories. Experiments are conducted on a dataset of 3,929 brain MRI images, evaluating the impact of model depth and fine-tuning strategies. The results show that ResNet18 achieves a higher accuracy of 97% compared to 96% for ResNet50, demonstrating better generalization on limited medical data. The proposed framework enables fast, accurate, and cost-effective brain tumor detection, supporting early diagnosis and clinical decision-making.
Automatic brain tumor segmentation from magnetic resonance imaging (MRI) has become a fundamental task in computer-assisted diagnosis, treatment planning, and disease monitoring. Although numerous deep learning architectures have recently been proposed, objective comparisons remain challenging because published studies often employ different datasets, preprocessing strategies, training protocols, and evaluation procedures. This work presents a unified experimental benchmark for comparing representative convolutional neural networks (CNNs), Transformer-based models, and recent State Space Model (SSM) architectures under homogeneous experimental conditions. Five state-of-the-art three-dimensional segmentation models, including 3D U-Net, SegResNet, Swin UNETR, SegMamba, and SegMambaV2, are evaluated on two brain tumor segmentation datasets representing distinct clinical scenarios: intracranial meningioma segmentation (BraTS 2023) and post-treatment glioma segmentation (BraTS 2024). All architectures are trained using identical preprocessing, data augmentation, optimization strategies, and evaluation protocols to ensure a fair comparison. Performance is assessed using segmentation accuracy metrics together with computational cost indicators, including inference time and the size of each model. The results provide practical insights into the trade-offs between segmentation accuracy and computational efficiency, highlighting the suitability of different architectural paradigms for challenging three-dimensional brain tumor segmentation tasks.
Diego J. Torrejón, Luna Y. Hernández, Javier Sánchez