Shape-programmable Magnetic Soft Membranes for Mechanically Active Microchannels

Magnetically programmable soft elastomers enable complex shape morphing and locomotion dynamics in small scale soft robots under external magnetic fields. Benefiting from their programmed deformation and wireless actuation capabilities, magnetic soft robots have emerged as promising platforms for targeted drug delivery, especially in human gastrointestinal tract. However, achieving controlled directional liquid cargo release toward desired tissue interface while preserving the encoded shape morphing and locomotion capabilities remain a significant challenge. Here, we report a new design strategy that employs an optimized magnetization profile to enable controlled directional release of aqueous cargo without compromising shape morphing and locomotion capabilities. Magnetic soft robots with a specific spatially distributed magnetization profile allow directional alignment of the release interface with the orientation of the external magnetic field. This orientation control ensures active alignment of the release interface toward the intestinal wall prior to drug release. An interconnected microporous elastomer is embedded within the robot for aqueous cargo storage, while a thin microcrystalline wax layer seals the release opening hole to isolate the stored liquid cargo from external environment during transport. Triggered release is achieved by mechanically rupturing the wax sealing layer under a higher magnitude external magnetic field. Controlled directional flipping, locomotion, and triggered release are decoupled through external magnetic field's direction and strength. The controlled directional release strategy reported here integrates directional targeted liquid cargo release, shape morphing, and locomotion, which establishes the groundwork for target drug delivery in gastrointestinal tract applications.

Scalable control of pneumatic and fluidic networks remains fundamentally constrained by architectures that require continuous power input, dense external control hardware, and fixed routing topologies. Current valve arrays rely on such continuous actuation and mechanically fixed routing, imposing substantial thermal and architectural overhead. Here, we introduce the Switchable-polarity Electropermanent Magnet (S-EPM), a bistable magnetic architecture that spatially redistributes its external magnetic field through transient electrical excitation. By reconfiguring internal flux pathways within a composite magnet assembly, the S-EPM exchanges reinforced and weakened magnetic-field regions while maintaining bistable, zero-power state retention. We integrate this architecture into a compact pinch-valve to robustly control pneumatic and liquid media. This state-encoded magnetic control enables programmable fluidic networks, including decoders, hierarchical distribution modules, and a nonvolatile six-port routing array. By embedding functionality in persistent magnetic states rather than continuous power or static plumbing, this work establishes a scalable foundation for programmable fluidics and self-driving laboratories.

Functional magnetic composites capable of large deformation, load bearing, and multifunctional motion are essential for next-generation adaptive soft robots. Here, we present muscle-inspired magnetic actuators (MMA), additively manufactured from a thermoplastic/permanent magnet polyurethane/Nd2Fe14B (TPU/MQP-S) composite using laser powder bed fusion (LPBF). By tuning the laser-energy scale between 1.0 and 3.0, both mechanical stiffness and magnetic response are precisely controlled: the tensile strength increases from 0.28 to 0.99 MPa while maintaining 30-45% elongation at break. This process enables the creation of 0.5 mm-thick flexural hinges, which reversibly bend and fold under moderate magnetic fields without damage. Two actuator types are reported showing the system versatility. The elongated actuator with self-weight of 1.57 g, magnetized in its contracted state, achieves linear contraction under a 500 mT field, lifting 50 g (32x its own weight) and sustaining performance over at least 50 cycles. Equipped with anisotropic frictional feet, it supports movement of a magnetic crawling robot that achieves up to 100% locomotion success on textured substrates. The expandable actuator exhibits reversible opening and closing under a 300 mT field, reliably grasping and releasing different objects, including soft berries and rigid 3D printed geometries. It can also anchor in a tube while holding suspended 50 g loads. This work demonstrates a LPBF-based strategy to program both stiffness and magnetization within a single material system, enabling remotely driven, reconfigurable, and fatigue-resistant soft actuators. The approach opens new possibilities for force controlled, multifunctional magnetic soft robots for adaptive gripping, locomotion, and minimally invasive manipulation of biomedical tools.