Security and Privacy in Agentic AI: Grand Challenges and Future Directions

This paper presents a structured analysis of security challenges in long-horizon agentic AI systems. The study reviews existing threats, evaluation approaches, attack propagation mechanisms, and security frameworks. A taxonomy of security threats and a framework for analyzing attack propagation are proposed to support future research in agentic AI security

We take the position that agent security must be approached as a systems problem: the AI model powering the agent must be treated as an untrusted component, and security invariants must be enforced at the system level. Through this lens, efforts to increase model robustness (the dominant viewpoint in the community) are insufficient on their own. Instead, we must complement existing efforts with techniques from the systems security domain. Based on our experience as cybersecurity researchers in operating systems, networks, formal methods, and adversarial machine learning, we articulate a set of core principles, grounded in decades of systems security research, that provide a foundation for designing agentic systems with predictable guarantees. As evidence, we analyze eleven representative real-world attacks on agents and discuss how systems principles, if realized, could have prevented these attacks. We also identify the research challenges that stand in the way of implementing these principles in agents.

Agentic AI systems -- Large Language Models (LLMs) augmented with planning, tool use, memory, and long-horizon interactions -- can execute complex tasks autonomously, but their multi-step trajectories introduce new failure modes that challenge trustworthiness. This survey provides a focused examination of trustworthy agentic AI through two core dimensions that are critical for high-risk deployments: Safety and Robustness, and Privacy and System Security. For each dimension, we clarify key concepts, identify where risks emerge along the agent workflow, and summarize stage-targeted mitigation strategies. Other trustworthiness aspects (value alignment, transparency, fairness, and accountability) are discussed as relevant context rather than parallel chapters. To support consistent comparison and deployment decisions, we consolidate evaluation into a unified metrics-and-benchmarks hub, emphasizing both outcome and process signals (e.g., constraint violations, trace completeness, and adversarial success rates) and offering scenario-to-metric guidance for release gating. We conclude by outlining open challenges such as self-evolving agents, runtime monitoring and verification, privacy-preserving personalization, and the trust-utility trade-off, and present a case study of real-world security failures in open-source agentic systems. Our goal is to serve as a practical reference for researchers and practitioners building trustworthy agentic systems in high-stakes environments.