The complexities of patient-centred conversational artificial intelligence
Authors: João Matos, Olivia Buege, Donny Cheung, Gary S. Collins, Paula Dhiman, Nan Li, Bingyu Mao, Benjamin W. Nelson, +3 more
Organizations: Verily Health, Dallas, TX, USA · Centre for Statistics in Medicine, University of Oxford, Oxford, UK · Department of Applied Health Sciences, School of Health Sciences, University of Birmingham, Birmingham, UK · National Institute for Health and Care Research (NIHR) Biomedical Research Centre: Birmingham, Birmingham, University Hospitals Birmingham NHS Foundation Trust and University of Birmingham, Birmingham, UK · Division of Digital Psychiatry, Department of Psychiatry, Harvard Medical School and Beth Israel Deaconess Medical Center, Boston, MA, US
Consumer-facing health chatbots powered by large language models (LLMs) are increasingly used for symptom assessment. However, chatbot development and evaluation often rely on cooperative, articulate, simulated patients. We analysed 2,053 real patient-chatbot conversations and found that communication patterns and expression of emotions vary widely across users. We developed a patient simulator that separately models clinical content, emotional state, conversational strategy, and communication style. In a Turing-inspired evaluation of realism with 15 human graders, simulated conversations were nearly indistinguishable from real ones, with human graders achieving an accuracy of 55%. We used five distinct patient personae, across 1,164 clinician-graded cases, to evaluate the performance of four LLMs in urgency assessment. We found that communication style can significantly alter triage outcomes. Patient-centred conversational artificial intelligence must accommodate communication diversity: systems designed for idealised, rather than realistic, interactions risk underperforming and amplifying health disparities when deployed in the real world.