Co4ICF: Co-evolving Physics-Informed Surrogate and RL-based Pulse Optimizer for Inertial Confinement Fusion

Inertial confinement fusion (ICF) is a leading pathway toward clean energy, but each shot at the National Ignition Facility costs on the order of one million dollars, making accurate AI surrogates a high-value target. We study exogenous-driven ICF waveform prediction, where a 512-step neutron-rate diagnostic must be inferred directly from a laser pulse and target design parameters, with no historical response observed. The regime stresses standard time-series predictors with temporal sparsity (picosecond peak in a nanosecond window), input-output scale mismatch (under 300 real shots), and peak sensitivity (picosecond timing). We propose ICF-DLM, to our knowledge the first LM-based ICF predictor, combining (i) a physics-typed decomposition into yield $Y_{DT}$, peak timing $t_{\mathrm{peak}}$, and local waveform $w_{\mathrm{local}}$; (ii) bidirectional denoising that defers commitment to peak location; and (iii) a physics-driven PPO reward re-injecting metric structure across numeric tokens. On ICFBench (50K simulations + 232 experimental shots), ICF-DLM cuts peak-timing error from 11.6 to 9.2 steps over a matched autoregressive LLaMA-3-8B and outperforms classical sequence models and LLM-based time-series predictors. Beyond ICF, the recipe shows potential to address science domains with low data and sparse events.

Inertial Confinement Fusion (ICF) holds transformative promise for sustainable, near-limitless clean energy, yet remains constrained by prohibitively high costs and limited experimental opportunities. This paper presents Human-in-the-Loop Meta Bayesian Optimization (HL-MBO), a framework that integrates expert knowledge with few-shot, uncertainty-aware machine learning to accelerate discovery in data-scarce, high-stakes scientific domains. HL-MBO introduces a meta-learned surrogate model with an expert-informed acquisition function to recommend candidate experiments. To foster trust and enable informed decisions, HL-MBO also provides interpretable explanations of its suggestions. We show HL-MBO outperforms current BO methods on ICF energy yield optimization, as well as benchmarks in molecular optimization and critical temperature maximization for superconducting materials.

This paper documents the implementation and evaluation of a self-supervised denoising framework on Inertial Confinement Fusion (ICF) images corrupted by Multiplicative Uniform noise: the \emph{Log-Domain Noisier2Inverse} framework. This framework is developed and analysed in this work; the key theoretical result -- that minimising the log-domain self-supervised loss is equivalent to supervised learning in the transformed domain -- is presented with full proof. We document significant implementation challenges arising from the unique characteristics of ICF imagery, describe the fixes applied at each stage, and report final quantitative results. The log-domain approach with per-image JSON Uniform noise loading (VariantB) achieves the best result: a mean PSNR of $21.41\db$ and SSIM of $0.8358$, a $+19.46\db$ improvement over the noisy input baseline of $1.95\db$, substantially outperforming BM3D log-domain ($4.47\db$, SSIM $0.5181$) and Noise2Self ($4.75\db$, SSIM $0.0177$). VariantA, using fixed Gaussian noise loading, achieves $21.39\db$ PSNR and SSIM $0.8436$. Of the three evaluated methods, Log-Domain Noisier2Inverse and Noise2Self are entirely self-supervised during training, requiring no clean ground truth data; BM3D is a classical filter-based method requiring no training at all. The clean reference images are used solely for quantitative evaluation of all three methods.