Difference-Driven Gating: Adaptive Feature Fusion for U-Net Decoder

Medical image segmentation relies on the ability of encoder-decoder architectures to translate rich feature representations into accurate pixel-level predictions under challenging conditions such as low contrast, structural ambiguity, and scale variability. While recent advances in large-scale pretraining and transformer-based encoders have substantially improved feature extraction, segmentation accuracy remains constrained by decoder design, particularly in terms of cross-scale alignment, contextual integration, and boundary preservation. In this work, we revisit medical image segmentation from a decoder-centric perspective and propose a context-aware gated decoder that systematically regulates feature fusion and contextual aggregation throughout the decoding process. The proposed decoder integrates lightweight multi-scale channel recalibration, gated skip fusion with spatial competition and a global context aggregation mechanism that injects encoder-wide information into intermediate decoding stages. This design enables effective translation of strong pretrained encoder representations into spatially consistent predictions. Extensive experiments across 11 medical image segmentation benchmarks validate the effectiveness and demonstrate that the proposed approach consistently outperforms strong baselines while remaining computationally practical. Code: https://github.com/saadwazir/MedCAGD

Deep Unfolding Network-based methods have emerged as effective solutions for multi-source image fusion by combining model-driven iterative optimization with data-driven deep learning. However, most existing deep unfolding image fusion methods are derived from alternating minimization, which updates the features of different modalities separately. This design introduces considerable computational and memory overhead, limiting deployment on resource-constrained edge devices. To address this issue, we propose CDNet, a lightweight Combined Dictionary Unfolding Network for multi-source image fusion. Rather than introducing a new sparse coding prior or empirically compressing an existing fusion network, CDNet translates the unique-common decomposition prior of coupled dictionary learning into a structurally constrained joint unfolding architecture. The resulting CDBlock follows a block-sparse interaction topology and performs a model-derived joint update of common and modality-specific representations, thereby streamlining feature learning and improving efficiency.In addition, we design a compact High- and Low-frequency Image Fidelity loss for unsupervised training without ground-truth images. We evaluate CDNet on four tasks, including multi-exposure image fusion, infrared and visible image fusion, medical image fusion, and infrared and visible image fusion for semantic segmentation. Experimental results show that CDNet achieves competitive or superior fusion performance with high efficiency. For infrared and visible image fusion, CDNet outperforms competing methods on four of six metrics on the TNO dataset and five of six metrics on the RoadScene dataset. In particular, it surpasses the second-best method by 1.23 dB and 1.59 dB in PSNR on TNO and RoadScene, respectively.

Many dense prediction networks rely on additive feature transformations and model higher-order feature interactions only implicitly. Product units provide an explicit mechanism for multiplicative feature modeling, but their logarithmic--exponential formulation can cause numerical instability, which has limited their use in deep dense prediction networks. In this work, we propose Product-Unit U-Net (PU-UNet), a residual U-Net that integrates stable product-unit residual blocks into rich low-resolution stages for medical image segmentation. The proposed formulation combines smooth positivity mapping with log-domain clipping, enabling stable multiplicative feature learning with negligible computational overhead. On ISIC 2018, Kvasir-SEG, and BUSI, PU-UNet achieves Dice scores of 0.942, 0.959, and up to 0.925, respectively. Compared with a matched Residual U-Net baseline, PU-UNet consistently improves Dice and IoU while keeping parameters, FLOPs, and inference latency nearly unchanged, and reduces the image-level false-positive rate on normal BUSI cases from 0.077 to zero. Ablation studies suggest that the gains are associated with product-unit interactions, are strongest under low-resolution placement, and benefit from the proposed stabilization design. These results suggest that stable product-unit residual learning can be an effective way to enhance U-Net-style segmentation networks with explicit multiplicative interactions.