Automated Multilabel Mpox Research Classification with Explainable Transformer Models

How should natural language processing models be selected and adapted for global health literature in environments where annotated data and computational resources are limited? This thesis investigates these challenges through experiments on semantic tag discovery, named entity recognition (NER), and multi-label topic classification. First, skip-gram word2vec models trained on progressively larger specialized corpora are compared with BioWordVec to assess how corpus size and domain context influence tag discovery. Vocabulary coverage and qualitative evaluation indicate that broader coverage does not necessarily yield more useful domain-specific associations. The analysis then turns to entity extraction, comparing convolutional spaCy models with a RoBERTa-based transformer on 1,000 annotated sentences. Under a lenient scoring protocol, the transformer achieves 0.80 micro-F1 versus 0.65-0.69 for convolutional models, but takes 82 seconds rather than 5-6 seconds. This trade-off motivates fine-tuning convolutional models and integrating a disease recognizer that achieves 81.33% test F1 on the NCBI Disease Corpus. Combined with PDF preprocessing, entity filtering, and MeSH enrichment, the resulting pipeline supports document-level indexing. To complement entity extraction with thematic annotation, MiniLM-based few-shot classification is compared with BART-MNLI zero-shot inference across 50 topics and 1,000 handcrafted test sentences. BART-MNLI achieves 95.2% single-label accuracy versus 59%; reported multi-label accuracies are 88% and 32% under partly manual assessment. However, its higher inference cost limits practical integration. The results show where domain specialization and lightweight adaptation offer practical value, and where transformer accuracy justifies higher inference costs, providing an empirical basis for building knowledge systems under resource constraints.

Large-scale multi-label text classification assigns a small subset of relevant labels to each document from a vocabulary containing thousands or tens of thousands of candidate labels. Although pretrained language models have improved semantic text representations, most representation-based approaches center their prediction pipelines on a primary encoder or combine auxiliary features within a single ranker. The complementarity between heterogeneous language models therefore remains insufficiently explored. We propose DualMLC, a dual-branch framework that processes the same document through an autoregressive decoder-only language model and a bidirectional encoder. Each branch maintains its own representation pathway and independently estimates relevance scores over the shared label space. DualMLC combines the two score vectors through late logit fusion, allowing shared evidence to reinforce relevant labels and branch-specific evidence to compensate for limitations in the other branch's representation. DualMLC achieves state-of-the-art results on three widely used large-scale multi-label text classification benchmarks. Ablation results further confirm that integrating the heterogeneous predictors produces stronger rankings than either branch alone. The source code is publicly available at https://github.com/huiyegit/DualMLC.

Multi-label image classification (MLIC), a fundamental task in computer vision, focuses on identifying multiple objects or concepts within an image, underpinning numerous read-world applications, such as autonomous driving, disease diagnosis, recommendation system, and mobile service robot. Over the past decade, deep learning paradigms based on convolutional neural networks, recurrent neural networks, and Transformers have significantly advanced this field, owing to their powerful capability in visual representation and relationship modeling. These advances have markedly improved the robustness, scalability, and generalization ability of MLIC models across diverse datasets and application domains. In this survey, we provide a comprehensive review of the deep learning-based literature on MLIC. Concretely, we first revisit the background, including problem definition, datasets, backbones and evaluation metrics. Next, we develop a plausible taxonomy for the deep learning-based MLIC approaches, organizing them into six groups: region-oriented methods, label-oriented methods, architecture-oriented methods, representation-oriented methods, learning-oriented methods, and data-oriented methods. Finally, we provide an insightful exposition of the underlying learning game in MLIC and its implications for other vision domains, and we empirically summarize the key challenges and research directions in MLIC while outlining promising avenues for future development. We believe this survey offers the research community a holistic and systematic perspective on MLIC, thereby facilitating subsequent exploration and innovation in this field and beyond.