cs.AIAug 5, 2026

NeuMoSync: End-to-End Neuromodulatory Control for Plasticity and Adaptability in Continual Learning

Authors: Seyed Roozbeh Razavi RohaniKhashayar KhajaviWesley ChungMandana SamieiMo Chen

Organizations: Department of Computer Science Simon Fraser University · Department of Computer Science McGill Univeristy, Mila - Quebec AI Institute

Abstract

Continual learning (CL) requires models to learn tasks sequentially, yet deep neural networks often suffer from plasticity loss and poor knowledge transfer, which can impede their long-term adaptability. Drawing high-level inspiration from global neuromodulatory mechanisms in the brain, we introduce Neuromodulation and Synchronization (NeuMoSync), a novel architecture that integrates dynamic, neuron-specific modulation into deep neural networks to enhance their adaptability and plasticity. NeuMoSync extends standard neural network architectures with learnable feature vectors for each neuron that track network-wide historical context and with a module operating at a higher level of abstraction. This module synthesizes neuron-specific signals, conditioned on both current inputs and the network's evolving state, to adaptively regulate activation dynamics and synaptic plasticity. Evaluated on diverse CL benchmarks, including memorization (Random Label CIFAR-10 and Random Label MNIST), concept drift (Shuffle CIFAR-10 and Shuffle Mini-ImageNet), class-incremental learning (Class Split ImageNet and Class Split CIFAR-100), and domain-incremental learning (Permuted MNIST), NeuMoSync demonstrates strong performance in retaining plasticity and achieves improvements in both forward and backward adaptation compared with existing methods. Ablation studies validate the necessity of each component, while analysis of the learned modulatory signals reveals interpretable coordination patterns across tasks. Our work underscores the potential of integrating global coordination mechanisms into deep learning systems to advance robust, adaptive continual learning. The code is publicly available at https://github.com/RoozbehRazavi/NeuMoSync.

Explore similar work

May 14, 2026cs.LG

MoRe: Modular Representations for Principled Continual Representation Learning on Sequential Data

Continual learning requires models to adapt to new data while preserving previously acquired knowledge. At its core, this challenge can be viewed as principled one-step adaptation: incorporating new information with minimal interference to existing representations. Most existing approaches address this challenge by modifying model parameters or architectures in a supervised, task-specific manner. However, the underlying issue is representational: tasks require distinct yet structured representations that can be selectively updated without disrupting representations, while structure should reflect intrinsic organization in the data rather than task boundaries. In sequential data, time-delayed dependencies provide a natural signal for uncovering this organization, revealing how fundamental representations give rise to more specific ones. Inspired by the modular organization of the human brain, we propose MoRe, a framework that identifies modularity in the representation itself rather than allocating it at the architectural level. MoRe decomposes knowledge into a hierarchy of fundamental and specific modules with identifiability guarantees, enabling principled module reuse, alignment, and expansion during adaptation while preserving old modules by construction. Experiments on synthetic benchmarks and real-world LLM activations demonstrate interpretable hierarchical structure, improved plasticity-stability trade-offs, suggesting MoRe as a principled foundation for continual adaptation
Jiaqi Sun, Boyang Sun, Rasmy M. H. +2
Apr 29, 2026cs.LG

NeuroPlastic: A Plasticity-Modulated Optimizer for Biologically Inspired Learning Dynamics

Optimization algorithms are fundamental to modern deep learning, yet most widely used methods rely on update rules based primarily on local gradient statistics. We introduce NeuroPlastic, a plasticity-modulated optimizer that augments gradient-based updates with an adaptive multi-signal modulation mechanism inspired by multi-factor synaptic plasticity, a concept from neurobiology. NeuroPlastic dynamically scales gradient updates using interacting components that capture gradient, activity-like, and memory-like statistics, forming a lightweight modulation layer compatible with standard deep learning training pipelines. Across image classification benchmarks, NeuroPlastic consistently improves over a controlled gradient-only ablation, with more pronounced gains on the Fashion-MNIST benchmark and in reduced-data regimes. In transfer experiments on CIFAR-10 with ResNet-18, the method remains stable and competitive without retuning. These results suggest that multi-signal plasticity-inspired modulation can provide a useful extension to conventional gradient-driven optimization, particularly when learning signals are limited or noisy, and offer a promising direction for gradient-based methods in deep learning.
Douglas Jiang, Yuechen Wang, Jiayi Wang +3
May 18, 2026cs.LG

MANGO: Meta-Adaptive Network Gradient Optimization for Online Continual Learning

In Online Continual Learning (OCL), a neural network sequentially learns from a non-stationary data stream in a single-pass with access only to a limited memory replay buffer. This contrasts sharply with off-line continual learning where training is multiple epoch dependent on large datasets. The main challenge faced by OCL is to overcome catastrophic forgetting of past tasks (stability) while learning new ones efficiently (plasticity). Existing methods counter forgetting via replay-based rehearsal, output level distillation, fixed regularization, or meta-learning on the current data. However, these methods have limitations: rehearsal introduces a stored sample bias; distillation operates on output-distributions without modulating parameter updates; fixed-regularization penalizes parameters irrespective of sensitivity; stream-only meta-learning lacks a feedback controlled parameter update. We propose Meta-Adaptive Network Gradient Optimization (MANGO), an OCL framework that balances stability-plasticity via gradient-gating and meta-learned regularization. Gradient-gating scales parameter updates based on sensitivity, preventing destructive updates. Meta-learned regularization adapts stability coefficients, evaluating the effect of parameter update on replay. In MANGO, replay acts as both a training signal and a forgetting evaluator. We evaluated our method on three standard OCL benchmark datasets. MANGO outperforms strong baselines, achieving state-of-the-art results with consistent performance across replay sizes. In domain incremental learning on CLEAR-10 and class incremental learning on CIFAR-100 and Tiny-ImageNet, it achieves highest accuracy among all baselines and achieves positive Backward Transfer, overcoming forgetting on CLEAR-10.
Ankita Awasthi, Marco Apolinario, Kaushik Roy