Real-world image generation often involves multi-turn editing, where users iteratively modify small regions while most image content remains unchanged. However, existing diffusion transformer (DiT)-based editing pipelines recompute the entire image at every turn, causing substantial redundant computation. Existing DiT acceleration methods further ignore semantic correspondence across prompts, leading to unnecessary recomputation or unsafe reuse that harms editing quality. To address this, we propose RegionCache, a semantic-aware reuse framework for multi-turn image editing that selectively reuses diffusion states from unchanged regions. RegionCache detects reusable regions through semantic overlap between consecutive prompts and cross-attention localization, and adopts an adaptive reuse schedule based on prompt similarity and contextual consistency. Experiments on PixArt-alpha demonstrate that RegionCache achieves 1.43x--2.55x end-to-end speedup while maintaining comparable image quality. Code is available at https://github.com/hebutBryant/RegionCache.