XVAE-WMT: Explainable Wavelet-Temporal Variational Autoencoder for Blind Source Separation of Heart and Lung Sounds

Cardiovascular diseases (CVDs) are the leading cause of death worldwide, accounting for approximately 17.9 million deaths each year. Early detection is critical, creating a demand for accurate and inexpensive pre-screening methods. Deep learning has recently been applied to classify abnormal heart sounds indicative of CVDs using synchronised phonocardiogram (PCG) and electrocardiogram (ECG) signals, as well as multichannel PCG (mPCG). However, state-of-the-art architectures remain underutilised due to the limited availability of synchronised and multichannel datasets. Augmented datasets and pre-trained models provide a pathway to overcome these limitations, enabling transformer-based architectures to be trained effectively. This work combines traditional signal processing with denoising diffusion models, WaveGrad and DiffWave, to create an augmented dataset to fine-tune a Wav2Vec 2.0-based classifier on multimodal and multichannel heart sound datasets. The approach achieves state-of-the-art performance. On the Computing in Cardiology (CinC) 2016 dataset of single channel PCG, accuracy, unweighted average recall (UAR), sensitivity, specificity and Matthew's correlation coefficient (MCC) reach 92.48%, 93.05%, 93.63%, 92.48%, 94.93% and 0.8283, respectively. Using the synchronised PCG and ECG signals of the training-a dataset from CinC, 93.14%, 92.21%, 94.35%, 90.10%, 95.12% and 0.8380 are achieved for accuracy, UAR, sensitivity, specificity and MCC, respectively. Using a wearable vest dataset consisting of mPCG data, the model achieves 77.13% accuracy, 74.25% UAR, 86.47% sensitivity, 62.04% specificity, and 0.5082 MCC. These results demonstrate the effectiveness of transformer-based models for CVD detection when supported by augmented datasets, highlighting their potential to advance multimodal and multichannel heart sound classification.

Text-guided sound separation enables flexible audio editing, assistive listening, and open-domain source extraction, but systems such as AudioSep remain too expensive for low-latency edge or codec-mediated deployment. Existing neural audio codec separators are efficient, yet largely restricted to fixed stems or closed taxonomies. We introduce CodecSep, a prompt-driven universal sound separation framework that extracts sources directly in neural audio codec latent space. CodecSep combines a frozen DAC backbone with a lightweight FiLM-conditioned Transformer masker driven by CLAP text embeddings, enabling open-vocabulary separation while preserving codec-native efficiency. Across dnr-v2 and five open-domain benchmarks, CodecSep consistently improves over AudioSep in SI-SDR, remains competitive in ViSQOL, and achieves clear gains in human MOS-LQS. Controlled analyses show that fine-grained prompts outperform coarse labels, and that explicit latent masking is substantially more effective than decoder-style latent generation in codec space. Qualitative diagnostics show that neural audio codec latents retain source-dependent structure, which CodecSep exploits mainly through channel-wise source-conditioned modulation. CodecSep also provides a practical code-stream deployment path. When audio is transmitted as neural audio codec codes, CodecSep maps codes to embeddings, separates directly in codec space, and outputs waveforms or re-quantized codes, avoiding the decode-separate-re-encode loop. In this regime, CodecSep requires only 1.35 GMACs end-to-end: about 54 times less compute than AudioSep in the same pipeline and 25 times lower separator-only compute, with much lower latency and memory. More broadly, CodecSep offers a blueprint for codec-native downstream audio processing.

In this paper, we introduce Synthetic Heart Sound Detection (SHAC), a task aimed at identifying phonocardiograms (PCGs) synthesized using neural audio codecs (NACs). To facilitate research in this direction, we release CARDIOFAKE, the first benchmark dataset for SHAC containing both real and codec-synthesized PCGs. We benchmark spectral representations (MFCC, LFCC) and self-supervised learning (SSL) representations (e.g., WavLM) for the task. Furthermore, we propose GROOT, a fusion framework that integrates spectral and SSL features for leveraging their complementary behavior. Experiments show that GROOT, combining MFCC and WavLM, achieves state-of-the-art performance, outperforming individual representations and competitive baselines.