More Than Just Access: Generative AI as Communication Intermediary for Blind and Low-Vision Users

Computer-use agents are emerging as a paradigm for agentic human-AI interaction, combining language reasoning with multi-modal interface grounding to operate GUIs. Yet their effectiveness for blind screen-reader users in real-world desktop workflows remains unclear. We present a three-week diary study with 8 blind users using OLLA, a screen-reader-accessible CUA prototype, collecting 1,258 commands across 12 applications with screenshots, UI trees, model responses, and action traces. We evaluate GPT-5 during deployment and re-execute the same commands with four additional models. GPT-5 achieved the highest success rate at 52.5%. Trace analysis reveals grounding, planning, constraint-tracking, and termination failures, while interviews reveal beyond-automation needs.

Visual diagrams, figures, and tables are central to scientific papers, and convey information beyond what is captured in text. While blind or low-vision (BLV) scientists have traditionally relied on static alternative text to access figures in papers, the rise of artificial intelligence (AI) has made interactive question-answering (QA) a feasible paradigm for visual exploration; yet little is known about how scientists use visual QA in practice or how to improve its accessibility. In this work, we interview five BLV and five sighted scientists across different STEM fields to understand how they use two AI tools, ChatGPT and Gemini, to query multimodal scientific documents. Our findings characterize how scientists review multimodal content, including existing practices (along with accessibility workarounds) for engaging with visuals, and feedback on the suitability of AI-generated responses to multimodal queries. We further find that vague or incomplete image descriptions, as well as incorrect AI outputs more broadly, can cause both BLV and sighted scientists to abandon AI workflows. To support future research, we additionally contribute a dataset of 115 queries and responses from our participants' interactions with the AI tools for papers in their field. We close by discussing implications for AI-powered scientific QA systems, emphasizing considerations for access across abilities and domains.

Assistive agents for Blind and Visually Impaired (BVI) users require accessibility alignment as a first-class design objective. Despite rapid progress in agentic AI, most systems are designed and evaluated under assumptions of sighted interaction, low-cost verification, and tolerable trial-and-error, leading to systematic failures in assistive scenarios that cannot be resolved by model scaling or post-hoc interface adaptations alone. Drawing on an analysis of 778 assistance task instances from prior work, we show that current agentic AI remain prone to failure in assistive scenarios due to mismatches between sighted-user design assumptions and the verification, risk, and interaction constraints faced by BVI users. We argue that accessibility should be treated as an alignment problem rather than a peripheral usability concern. To this end, we introduce accessibility alignment and propose a lifecycle-oriented design pipeline for accessibility-aligned assistive agents, spanning user research, system design, deployment and post-deployment iteration. We conclude that BVI-centered assistive tasks provide a critical stress test for agentic AI and motivate a broader shift toward inclusive agent design.