Unlocking Cross-Scenario Physical Layer Security: A Mixture-of-Experts Framework with Generative Diffusion Models

In sixth-generation (6G) networks, billions of cyber-physical systems (CPSs) - autonomous vehicles, smart grids, industrial robots, and remote-surgical equipment - will run over ultra-reliable low-latency slices, collapsing the gap between a remote breach and physical harm to milliseconds, a budget perimeter firewalls and centralised security operations centres cannot meet. This survey reframes 6G CPS security as a closed-loop, AI-native pipeline that senses at the multi-access edge computing (MEC) tier, using minute-scale call-detail records (CDRs) for baseline learning and sub-millisecond RAN/Open-RAN (O-RAN) telemetry for the latency-critical path. It decides locally with compressed deep models, mitigates network-wide via SDN, NFV, and O-RAN controllers, and retrains through federated learning (FL) and digital-twin (DT) replay. We formalise a per-slice, tail-bounded latency contract on the sense, detect, and mitigate stages, enforced at a slice-dependent tail percentile (p99 for safety-critical URLLC slices). Organising 128 peer-reviewed studies (2017-2026) under a PRISMA 2020 protocol, we (i) map the 6G/CPS threat surface to MITRE ATT&CK and a CDR-observable feature space; (ii) unify edge anomaly detection and DDoS classification across twelve datasets and statistical, graph, and transformer models; (iii) synthesise SDN/NFV/O-RAN primitives into one closed-loop reference architecture; (iv) treat FL, large language models (LLMs), DT, post-quantum cryptography (PQC), zero-trust architecture (ZTA), and explainable AI as cross-cutting enablers, not parallel pillars; and (v) consolidate open problems into five directions spanning data, latency, trust, standardisation, and evaluation.

Emerging 6G wireless networks are expected to operate across diverse deployment scenarios, where variations in network topology, user mobility, traffic demand, and radio conditions challenge the scalability of conventional radio resource management (RRM). While offline reinforcement learning (RL) methods have demonstrated strong decision-making capabilities, learning a single policy that performs consistently across heterogeneous wireless environments remains difficult due to conflicting optimization objectives and limited model specialization. These challenges become particularly pronounced in coordinated multipoint (CoMP) transmission, where selecting the optimal serving-cell combination requires sequential decision-making under evolving network conditions. This paper presents the Wireless Sparse Decision Transformer with Mixture of Experts (WiSDoM), a sparse multi-task offline RL framework for adaptive multi-cell selection. WiSDoM combines Decision Transformers (DTs) with a Mixture-of-Experts (MoE) architecture that dynamically activates specialized experts according to task characteristics. This MoE mechanism improves model capacity without proportionally increasing inference cost, mitigates negative transfer, and enables expert specialization across tasks. WiSDoM is trained jointly on diverse network configurations spanning multiple base station and user equipment densities, mobility levels, and scheduler policies. Experimental results show that WiSDoM consistently outperforms heuristic methods, single-task models, and conventional multi-task DTs, improving quality of experience (QoE) by up to 55% while activating approximately one-third of the parameters of its dense counterpart during inference. Furthermore, WiSDoM exhibits strong task generalization and efficiently adapts to unseen wireless scenarios through few-shot prompting without retraining or fine-tuning.

Conventional wireless networks rely on instantaneous channel state information (CSI) and react to channel variations without explicitly modeling the physical environment, limiting their ability to handle blockage, mobility, and interference in dynamic deployments. Paradigms such as Integrated Sensing and Communication (ISAC) add sensing capabilities but lack explicit environment modeling and decision-making. In this article, we propose Physical-AI: a new architecture for environment-aware wireless networking, where radio signals enable sensing, modeling, and interaction with the environment in addition to data transmission. The framework proposes a self-supervised spatiotemporal radio foundation model for transforming distributed radio observations into a shared latent environmental representation. Multiple inference heads operate on this representation to estimate key environmental properties, including blockage, user distribution, mobility dynamics, and interference structure. A task-specific neural decision layer maps this representation to proactive, context-aware control actions. By integrating perception, world modeling, and decision-making in a closed loop, the proposed framework goes beyond ISAC and establishes Physical-AI as a promising architecture for intelligent 6G systems. Simulation results show that the proposed predictive framework reduces outage probability and blockage-response latency, particularly under increasing beam-switching delays.