Does DCGAN-Based Synthetic Augmentation Improve Brain Tumor MRI Classification? An Empirical Study
Authors: Irhum Jawad Khan, Talha bin Aslam
Organizations: School of Electrical Engineering and Computer Science (SEECS) National University of Sciences and Technology (NUST) Islamabad, Pakistan · Independent Researcher Islamabad, Pakistan
Generative adversarial networks (GANs) are increasingly used to augment medical imaging datasets, but synthetic images do not necessarily provide downstream classification benefits. This study investigates whether class-specific Deep Convolutional Generative Adversarial Network (DCGAN) augmentation improves brain tumor classification when the classifier and evaluation set are held constant. Experiments were conducted on 7,200 brain magnetic resonance imaging (MRI) scans across four classes: glioma, meningioma, pituitary tumor, and no tumor. For each class, 1,400 real images were used for training and 400 were reserved for testing. A baseline Swin Transformer classifier was trained using only the real training images and compared with a second model trained using the same real images augmented with 500 DCGAN-generated images per class. Both conditions were evaluated on the identical held-out test set. The two models achieved the same overall accuracy of 96%, while macro F1 remained effectively unchanged and ROC-AUC decreased slightly from 0.987 to 0.982 after augmentation. Class-level analysis showed small redistributions in errors rather than a consistent performance gain. FID values between real and synthetic images ranged from 209.15 to 314.27, indicating substantial distributional differences under the adopted evaluation setup. These results suggest that synthetic augmentation should not be assumed to improve medical image classification and should instead be evaluated for both distributional fidelity and downstream task utility.
Generative augmentation is often proposed as a remedy for small medical-image datasets, but synthetic images are only useful when they improve downstream task performance. "Augmentation" here means synthetic supplementation: GAN-generated samples added to the real training pool, not geometric or photometric transforms of existing images. Twelve class-plane StyleGAN2-ADA generators were trained on constrained BRISC 2025 partitions to test whether their output, with or without InceptionV3 feature-space filtering, improves held-out tumour classification across three classifier families: a random forest (RF) on InceptionV3 features, a compact two-headed convolutional neural network (CNN), and MobileViTV2, a mobile hybrid convolutional-transformer. Each was evaluated at 1:1 and 1:2 real-to-synthetic ratios. An independent GPT-5.5 blind test placed gated real-versus-synthetic discrimination at 57.73% (95% CI: 54.48--60.92%) on the model-legible subset -- modestly above chance. The RF classifier did not benefit from the synthetic MRIs. The CNN showed consistent mean gains that did not survive Holm correction. MobileViTV2 showed the clearest benefit: filtered 1:1 augmentation improved tumour classification accuracy by 1.02% absolute (95% CI: 0.54--1.54%; Holm-corrected p = 0.0104). A secondary efficiency analysis found that every augmented CNN condition selected its checkpoint 42--64% earlier than baseline, while compute-matched MobileViTV2 runs reached selection after 50--67% fewer real-data epochs. Overall, augmentation utility was found to be architecture- and ratio-dependent, not guaranteed by visual fidelity alone.
Medical image classification is often constrained by limited labeled data, motivating generative augmentation; recently, quantum generative models have been proposed for this purpose, frequently reporting accuracy gains. However, such claims are typically based on single training runs, do not match the parameter budgets of the quantum and classical generators, and do not characterize the data regime in which any benefit appears. We present a controlled benchmark that isolates the contribution of a quantum generator to brain-MRI augmentation. Images are encoded into a KL-regularized latent space in which a conditional Wasserstein GAN with gradient penalty is trained using either a variational quantum generator or a classical generator of near-identical parameter count (1648 vs. 1632). Synthetic samples are decoded and used to augment a pretrained classifier across labeled data fractions from 5% to 100%, evaluated over eight random seeds with paired significance testing (with multiple-comparison correction) and with intraset diversity and latent-distribution analyses. Across all fractions, no augmentation variant significantly outperforms real-data-only training, and the quantum and classical generators are statistically indistinguishable. Any low-data benefit behaves as regularization rather than faithful data expansion:synthetic samples are off distribution and severely mode collapsed precisely where data is scarce, and the quantum generator is no more diverse thanits classical counterpart. We release the protocol as a testbed for rigorous evaluation of quantum generative augmentation in medical imaging.
Syed Mujtaba Haider, Silvia Figini
Department of Political and Social Sciences, University of Pavia, Pavia, Italy
Generative Adversarial Networks (GANs) can help overcome data scarcity in computer vision tasks by generating additional training samples. In this work, we explore generative data augmentation in two low-resource domains: Bangla handwritten character recognition and chest X-ray image analysis. We use DCGAN-based models trained on 64x64 images to generate synthetic samples and evaluate their quality using Inception Score (IS), Fréchet Inception Distance (FID), and visualization methods such as t-SNE and UMAP. To measure practical usefulness, we train image classifiers using real data and a combination of real and synthetic data. Experimental results show that synthetic augmentation improves data diversity and consistently increases classification performance in limited-data settings. We also investigate training stability techniques, including gradient penalty and spectral normalization, and perform ablation studies on synthetic-to-real data ratios and sample filtering strategies. In addition, we discuss challenges related to medical image evaluation, dataset licensing, and privacy concerns of synthetic data. Our approach is simple, reproducible, and provides a strong baseline for generative augmentation in resource-constrained imaging applications.
Md. Sohanuzzaman Soad, Mahady Al Hady, S M Rafiuddin Rifat +1
Department of Computer Science and Engineering University of Asia Pacific Dhaka, Bangladesh