Fisher Contrastive Learning to Mitigate Feature Suppression: A Case Study in Acute Promyelocytic Leukemia Diagnosis

Unsupervised feature selection seeks a compact subset of informative features without access to class labels, making feature utility difficult to define. Existing UFS methods therefore rely on indirect structural criteria, such as similarity preservation, locality, sparsity, cluster geometry, or reconstruction quality. In this paper, we instead study UFS through representation consistency and propose Inverted Contrastive Learning for Unsupervised Feature Selection (ICLFS), a feature-wise contrastive framework that reformulates UFS as a representation learning problem over features rather than samples. ICLFS first inverts the data matrix so that each feature is represented by its sample-profile vector, then constructs multiple masked positive views together with a shuffled negative view, and learns projector-space representations that remain consistent across these structured perturbations under an InfoNCE-based objective. Motivated by recent findings that cosine-based and InfoNCE-based training affect embedding norms, we use projector-space embedding magnitude as the saliency signal for ranking features. The resulting norm-based ranking is subsequently refined through Laplacian-Gated Ranking Correction, which suppresses locally redundant candidates while preserving salient ones. Extensive experiments on 12 benchmark datasets show that ICLFS achieves the best clustering accuracy on 10 datasets against both classical and neural baselines under the standard clustering-based UFS evaluation protocol, while remaining competitive on the other two. These results show that feature-wise contrastive representation consistency provides a strong and effective alternative to neighborhood, cluster, and reconstruction-based UFS formulations.

Self-supervised fine-tuning refines the embedding space of a pretrained language encoder without labels. However, the commonly used approaches are computationally expensive. Specifically, contrastive learning-based methods need multiview data and in-batch negative examples, while negative-free approaches require auxiliary graphs/networks. An interesting question arises: can self-supervised fine-tuning be done without relying on either additional negatives or graph data? To answer this question, we introduce SilK (Silhouette-guided K-means), which trains on a Cluster Validation Index, an internal measure of cluster quality without using labels. SilK clusters the corpus and then regresses a simplified silhouette toward a target value. Each document is compared only against the k cluster centroids, never against other documents, so the method needs no augmentation, no negative pairs and one view per document. On BERT-base, SilK trains 1.46x faster per epoch than the fastest baseline we evaluate and uses 45.4% less peak GPU memory than the leanest one. Under frozen-encoder linear probing, SilK stays competitive with the best baselines on three downstream tasks.

Deep learning-based AMC methods have achieved remarkable performance, but their practical deployment remains constrained by the high cost of labeled data. Although self-supervised learning (SSL) reduces the reliance on labels, existing SSL-based AMC methods often rely on task-agnostic pretext objectives misaligned with modulation classification, leading to representations entangled with nuisance factors such as symbol, channel, and noise. In this paper, we identify intra-instance modulation consistency as a task-aware structural prior, whereby different temporal segments of the same signal may differ in waveform while preserving the same modulation type, thus providing a principled cue for task-aligned self-supervision. Based on this prior, we propose Mod-CL, a Modulation consistency-based Contrastive Learning framework that constructs positive pairs from different temporal segments of the same signal instance, to encourage the model to learn shared modulation information while suppressing nuisance variations. We further develop a contrastive objective tailored to Mod-CL, which jointly exploits temporal segmentation and data augmentation to pull together views sharing the same modulation semantics while avoiding supervisory conflicts within each signal instance. Extensive experiments on RadioML datasets show that Mod-CL consistently outperforms strong baselines, especially in low-label regimes, achieving substantial improvements in linear probing accuracy.