Diffusion-Based Image Generation

We propose Ambient Dataloops, an iterative framework for refining datasets that makes it easier for diffusion models to learn the underlying data distribution. Modern datasets contain samples of highly varying quality, and training directly on such heterogeneous data often yields suboptimal models. We propose a dataset-model co-evolution process; at each iteration of our method, the dataset becomes progressively higher quality, and the model improves accordingly. To avoid destructive self-consuming loops, at each generation, we treat the synthetically improved samples as noisy, but at a slightly lower noisy level than the previous iteration, and we use Ambient Diffusion techniques for learning under corruption. Empirically, Ambient Dataloops achieve state-of-the-art performance in unconditional and text-conditional image generation and de novo protein design. We further provide a theoretical justification for the proposed framework that captures the benefits of the data looping procedure.

Substation meters play a critical role in monitoring and ensuring the stable operation of power grids, yet their detection of cracks and other physical defects is often hampered by a severe scarcity of annotated samples. To address this few-shot generation challenge, we propose a novel framework that integrates Knowledge Embedding and Hypernetwork-Guided Conditional Control into a Stable Diffusion pipeline, enabling realistic and controllable synthesis of defect images from limited data. First, we bridge the substantial domain gap between natural-image pre-trained models and industrial equipment by fine-tuning a Stable Diffusion backbone using DreamBooth-style knowledge embedding. This process encodes the unique structural and textural priors of substation meters, ensuring generated images retain authentic meter characteristics. Second, we introduce a geometric crack modeling module that parameterizes defect attributes--such as location, length, curvature, and branching pattern--to produce spatially constrained control maps. These maps provide precise, pixel-level guidance during generation. Third, we design a lightweight hypernetwork that dynamically modulates the denoising process of the diffusion model in response to the control maps and high-level defect descriptors, achieving a flexible balance between generation fidelity and controllability. Extensive experiments on a real-world substation meter dataset demonstrate that our method substantially outperforms existing augmentation and generation baselines. It reduces Frechet Inception Distance (FID) by 32.7%, increases diversity metrics, and--most importantly--boosts the mAP of a downstream defect detector by 15.3% when trained on augmented data. The framework offers a practical, high-quality data synthesis solution for industrial inspection systems where defect samples are rare.

Expert-annotated training data remains the critical bottleneck for AI in histopathology, particularly for rare pathologies where even dozens of cases may be unavailable. While data augmentation offers a solution, existing methods fail to generate sufficiently realistic lesion morphologies that preserve tissue-specific architectures. Here we present PathoGen, a diffusion-based generative model enabling controllable, high-fidelity lesion inpainting into benign histopathology images. We validate PathoGen across four datasets representing kidney, skin, breast, and prostate pathology. Quantitative assessment confirms PathoGen outperforms state-of-the-art baselines in image fidelity and distributional similarity. Evaluation by six expert pathologists revealed that synthetic images by PathoGen were only marginally distinguished from real tissue image slightly above chance (57.75% accuracy), demonstrating strong perceptual realism of PathoGen-generated lesions. PathoGen achieved the highest win rate (35.4%) when pathologists ranked generation quality against all baselines. Crucially, augmenting training sets with PathoGen-synthesized lesions improves segmentation Dice scores by up to 0.18 compared to traditional augmentations, with maximum benefit in data-scarce regimes. By simultaneously generating realistic morphology and pixel-level annotations, PathoGen effectively addresses both data scarcity and annotation cost, two critical bottlenecks in computational pathology development.

This paper studies the training-testing discrepancy (a.k.a. exposure bias) problem for improving the diffusion models. During training, the input of a prediction network at one training timestep is the corresponding ground-truth noisy data that is an interpolation of the noise and the data, and during testing, the input is the generated noisy data. We present a novel training approach, named MixFlow, for improving the performance. Our approach is motivated by the Slow Flow phenomenon: the ground-truth interpolation that is the nearest to the generated noisy data at a given sampling timestep is observed to correspond to a higher-noise timestep (termed slowed timestep), i.e., the corresponding ground-truth timestep is slower than the sampling timestep. MixFlow leverages the interpolations at the slowed timesteps, named slowed interpolation mixture, for post-training the prediction network for each training timestep. Experiments over class-conditional image generation (including SiT, REPA, and RAE) and text-to-image generation validate the effectiveness of our approach. Our approach MixFlow over the RAE models achieve strong generation results on ImageNet: 1.43 FID (without guidance) and 1.10 (with guidance) at 256 x 256, and 1.55 FID (without guidance) and 1.10 (with guidance) at 512 x 512.

In diffusion and flow-matching generative models, guidance techniques are widely used to improve sample quality and consistency. Classifier-free guidance (CFG) is the de facto choice in modern systems and achieves this by contrasting conditional and unconditional samples. Recent work explores contrasting negative samples at inference using a weaker model, via strong/weak model pairs, attention-based masking, stochastic block dropping, or perturbations to the self-attention energy landscape. While these strategies refine the generation quality, they still lack a reliable control over the granularity or difficulty of the negative samples, and target-layer selection is often fixed. We propose Exponential Moving Average Guidance (EMAG), a training-free mechanism that modifies attention at inference time in diffusion transformers, with a statistics-based, adaptive layer-selection rule. Unlike prior methods, EMAG produces harder, semantically faithful negatives (fine-grained degradations), surfacing difficult failure modes, enabling the denoiser to refine subtle artifacts, boosting the quality and human preference score (HPS) by +0.54 over CFG. We further demonstrate that EMAG naturally composes with advanced orthogonal guidance techniques, such as APG and CADS, further improving HPS.

Generating realistic cast shadows for inserted foreground objects requires reasoning about scene geometry and illumination. However, most learning-based approaches treat shadow generation as an image translation problem and capture these physical relationships only implicitly. This often results in misaligned or implausible shadows. Motivated by the physics of shadow formation, we introduce explicit geometric guidance for outdoor shadow generation. Given a composite image and a foreground object mask, we recover approximate scene geometry and estimate a dominant light direction to derive a coarse shadow estimate via geometric reasoning. While coarse, this estimate provides a spatial anchor for shadow placement. Because illumination cannot always be uniquely inferred from a single image, we predict confidence scores for both lighting and shadow cues and use them to regulate their influence during generation. These cues (shadow mask, light direction, and their confidence scores) condition a diffusion-based generator that refines the estimate into a realistic shadow. Experiments on DESOBAV2 show substantially improved shadow-region fidelity and localization, with an overall 23% lower shadow-region RMSE and 30% lower shadow-mask BER than the prior state-of-the-art method.

3D head stylization enables expressive reimagining of human faces for creative visual experiences in digital media. Existing 3D-aware methods often require computationally intensive optimization or per-style fine-tuning, limiting flexibility and user control. To overcome these challenges, we introduce StyleFusion360, a diffusion-based framework for multi-view consistent, identity-preserving 3D head stylization from a single style reference image, without per-style training. Our approach enhances the Style Fusion Attention mechanism with a style-conditioned key modulation mechanism that aligns content and style representations for fine-grained and controllable stylization. We further provide a user-controllable slider for adjusting stylization intensity. In addition, StyleFusion360 supports local multi-edit stylization, enabling targeted edits such as modifying hair or eyes independently. Extensive experiments on FFHQ and RenderMe360 demonstrate that StyleFusion360 produces high-quality, controllable, and visually compelling stylizations, outperforming state-of-the-art GAN- and diffusion-based methods across diverse style domains.

Anomaly generation is often framed as few-shot fine-tuning with anomalous samples, which contradicts the scarcity that motivates generation and tends to overfit category priors. We tackle the setting where no real anomaly samples or training are available. We propose Delta-Denoising (\textbf{DeltaDeno}), a training-free zero-shot anomaly generation method that localizes and edits defects by contrasting two diffusion branches driven by a minimal prompt pair under a shared schedule. By accumulating per-step denoising deltas into an image-specific localization map, we obtain a mask to guide the latent inpainting during later diffusion steps and preserve the surrounding context while generating realistic local defects. To improve stability and control, DeltaDeno performs token-level prompt refinement that aligns shared content and strengthens anomaly tokens, and applies a spatial attention bias restricted to anomaly tokens in the predicted region. Experiments on public datasets show that DeltaDeno achieves great generation, realism and consistent gains in downstream detection performance. Code will be made publicly available at https://github.com/CROVO1026/DeltaDeno.

Training data for class-conditional image synthesis often exhibit a long-tailed distribution with limited amount of images for tail classes. Such an imbalance causes mode collapse and reduces the diversity of synthesized images for tail classes. For class-conditional diffusion models trained with imbalanced data, we aim to improve the diversity and fidelity of tail class images without compromising the quality of head class images. We propose contrastive conditional-unconditional alignment (CCUA), which comprises two synergistic loss functions. Our first loss is an Alignment Loss (AL) that aligns class-conditional generation with unconditional generation at large timesteps. Alignment loss makes the denoising process insensitive to class conditions for the initial steps, which enriches tail classes through knowledge sharing from head classes. Secondly, we diversify unconditional generation via an Unsupervised Contrastive Loss (UCL) to increase the distance/dissimilarity among synthetic images. We combine the two losses to implicitly diversify conditional generation. Our framework is easy to implement as demonstrated on both U-Net based architecture and Diffusion Transformer. Our method outperforms vanilla denoising diffusion probabilistic models, score-based diffusion model, and alternative contrastive methods for class-imbalanced image generation across various datasets, in particular ImageNet-LT with 256$\times$256 resolution.