Modularity is the Bedrock of Natural and Artificial Intelligence

This paper bridges neuroscience and artificial intelligence to propose a cortically inspired blueprint for modular perceptual AI. While current monolithic models such as GPT-4V achieve impressive performance, they often struggle to explicitly support interpretability, compositional generalization, and adaptive robustness - hallmarks of human cognition. Drawing on neuroscientific models of cortical modularity, predictive processing, and cross-modal integration, we advocate decomposing perception into specialized, interacting modules. This architecture supports structured, human-inspired reasoning by making internal inference processes explicit through hierarchical predictive feedback loops and shared latent spaces. Our proof-of-concept study provides empirical evidence that modular decomposition yields more stable and inspectable representations. By grounding AI design in biologically validated principles, we move toward systems that not only perform well, but also support more transparent and human-aligned inference.

Humanity is a mosaic of multifaceted talents and needs, and any truly intelligent AI must reflect that richness. Yet the LLMs used by all are built by the few -- a centralized market of monolithic AI models structurally ill-suited to capture the diversity of human knowledge, reasoning, and values. Here we introduce scaling participation, a new paradigm in which modular, community-sourced AI systems are built from the bottom up through the contributions of diverse stakeholders. Participants contribute small models trained on their own interests and priorities; these models then collaborate in modular frameworks as compositional AI systems, repurposing existing collaboration algorithms for this bottom-up paradigm. Participatory AI systems outperform monolithic LLMs by up to 15.42% (95% CI: [10.09%, 21.13%]) across 15 tasks, such as reasoning and factuality, surpassing models with more parameters than all contributed components combined. Further experiments show that these systems are especially strong at representing diverse cultures, values, and communities, benefit from contributor diversity, substantially improve on each contributor's original priorities, and exhibit emergent capabilities that allow them to solve over 15% of problems where all individual models fail. Scaling participation provides a technical foundation, demonstrated here with academic contributors and benchmark evaluations, for transitioning from the monolithic status quo toward an open, bottom-up, and collaborative AI future.

Neuroscience and Artificial Intelligence (AI) have made impressive progress in recent years but remain only loosely interconnected. Based on a workshop convened by the National Science Foundation in August 2025, we identify three fundamental capability gaps in current AI: the inability to interact with the physical world, inadequate learning that produces brittle systems, and unsustainable energy and data inefficiency. We describe the neuroscience principles that address each: co-design of body and controller, prediction through interaction, multi-scale learning with neuromodulatory control, hierarchical distributed architectures, and sparse event-driven computation. We present a research roadmap organized around these principles at near, mid, and long-term horizons. We argue that realizing this program requires a new generation of researchers trained across the boundary between neuroscience and engineering, and describe the institutional conditions: interdisciplinary training, hardware access, community standards, and ethics, needed to support them. We conclude that NeuroAI, neuroscience-informed artificial intelligence, has the potential to overcome limitations of current AI while deepening our understanding of biological neural computation.